Description

  • Product name

    Recombinant Human AKR1C1 protein
    See all AKR1C1 proteins and peptides
  • Purity

    > 90 % SDS-PAGE.
    Purified by using conventional chromatography techniques.
  • Expression system

    Escherichia coli
  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      MGSSHHHHHH SSGLVPRGSH MDSKYQCVKL NDGHFMPVLG FGTYAPAEVP KSKALEATKL AIEAGFRHID SAHLYNNEEQ VGLAIRSKIA DGSVKREDIF YTSKLWCNSH RPELVRPALE RSLKNLQLDY VDLYLIHFPV SVKPGEEVIP KDENGKILFD TVDLCATWEA VEKCKDAGLA KSIGVSNFNR RQLEMILNKP GLKYKPVCNQ VECHPYFNQR KLLDFCKSKD IVLVAYSALG SHREEPWVDP NSPVLLEDPV LCALAKKHKR TPALIALRYQ LQRGVVVLAK SYNEQRIRQN VQVFEFQLTS EEMKAIDGLN RNVRYLTLDI FAGPPNYPFS DEY
    • Amino acids

      1 to 323

Specifications

Our Abpromise guarantee covers the use of ab93730 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    SDS-PAGE

  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.0154% DTT, 0.316% Tris HCl, 20% Glycerol

General Info

  • Alternative names

    • 2-dihydrobenzene-1
    • 2-diol dehydrogenase
    • 20 alpha (3 alpha) hydroxysteroid dehydrogenase
    • 20 ALPHA HSD
    • 20 alpha hydroxysteroid dehydrogenase
    • 20-alpha-HSD
    • 20-alpha-hydroxysteroid dehydrogenase
    • 20ALPHAHSD
    • 2ALPHAHSD
    • AK1C1
    • AK1C1_HUMAN
    • AKR1C1
    • Aldo keto reductase family 1 member C1
    • aldo-keto reductase C
    • Aldo-keto reductase family 1 member C1
    • Aldo-keto reductase family, 1 member 1
    • C9
    • Chlordecone reductase homolog
    • Chlordecone reductase homolog HAKRC
    • DD1
    • DD1/DD2
    • DDH
    • DDH1
    • Dihydrodiol dehydrogenase 1
    • Dihydrodiol dehydrogenase 1/2
    • dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase
    • dihydrodiol dehydrogenase isoform DD1
    • Dihydrodiol dehydrogenase, type 1
    • H37
    • HAKRC
    • HBAB
    • Hepatic dihydrodiol dehydrogenase
    • High affinity hepatic bile acid-binding protein
    • High-affinity hepatic bile acid-binding protein
    • Indanol dehydrogenase
    • MBAB
    • MGC8954
    • Trans-1
    • Trans-1,2 dihydrobenzene 1,2 diol dehydrogenase
    • Type II 3 alpha hydroxysteroid dehydrogenase
    see all
  • Function

    Converts progesterone to its inactive form, 20-alpha-dihydroxyprogesterone (20-alpha-OHP). In the liver and intestine, may have a role in the transport of bile. May have a role in monitoring the intrahepatic bile acid concentration. Has a low bile-binding ability. May play a role in myelin formation.
  • Tissue specificity

    Expressed in all tissues tested including liver, prostate, testis, adrenal gland, brain, uterus, mammary gland and keratinocytes. Highest levels found in liver, mammary gland and brain.
  • Sequence similarities

    Belongs to the aldo/keto reductase family.
  • Cellular localization

    Cytoplasm.
  • Information by UniProt

Images

  • 15% SDS Page analysis of ab93730 (3 µg).

References

ab93730 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab93730.
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