The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Specific activity is approximately 0.25 – 0.3 units/mg. Enzymatic activity was confirmed by measuring the amount of enzyme catalyzing the oxidation of 1 micromole NADPH per minute at 25°C. Specific activity was expressed as units/mg protein.
>95% by SDS-PAGE .
Concentration information loading...
Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 8.00 Constituents: 0.05% DTT, 0.32% Tris HCl, 20% Glycerol
This product is an active protein and may elicit a biological response in vivo, handle with caution.
AFB1 aldehyde reductase 1
Aflatoxin aldehyde reductase
Aflatoxin B1 aldehyde reductase member 2
Aflatoxin beta1 aldehyde reductase
Aldo keto reductase family 7
Aldo keto reductase family 7 member A2
Aldo keto reductase family 7 member A2 aflatoxin aldehyde reductase
Aldo keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
Succinic semialdehyde reductase
Catalyzes the NADPH-dependent reduction of succinic semialdehyde to gamma-hydroxybutyrate. May have an important role in producing the neuromodulator gamma-hydroxybutyrate (GHB). Has broad substrate specificity. Has NADPH-dependent aldehyde reductase activity towards 2-carboxybenzaldehyde, 2-nitrobenzaldehyde and pyridine-2-aldehyde (in vitro). Can reduce 1,2-naphthoquinone and 9,10-phenanthrenequinone (in vitro). Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen.
Detected in brain, liver, small intestine and testis, and at lower levels in heart, prostate, skeletal muscle and spleen. Detected in kidney proximal and distal tubules, endothelial cells lining the Bowman's capsules and some cysts. Detected at low levels in lung and pancreas (at protein level). Widely expressed.