Recombinant human alpha 2a Adrenergic Receptor protein (ab54291)
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Overview
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Product nameRecombinant human alpha 2a Adrenergic Receptor protein
See all alpha 2a Adrenergic Receptor proteins and peptides -
Protein lengthFull length protein
Description
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NatureRecombinant
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SourceBaculovirus infected Sf9 cells
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Amino Acid Sequence
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SpeciesHuman
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SequenceMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFG NVLVIIAVFT SRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGY WYFGKAWCEIYLALDVLFCTSS IVHLCAISLDRYWSITQAIEYNLKRT PRRIKAIIITVWVISAVISFPPLISIEKKGGGGG PQPAEPRCEINDQK WYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVA AP PGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALD LEESSSSD HAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGAT GIGTPAAGPGEERVGAAKAS RWRGRQNREKRFTFVLAVVIGVFVVCWF PFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSS LNPVIYTIFNHDFRRA FKKILCRGDRKRIV
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Associated products
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Related Products
Specifications
Our Abpromise guarantee covers the use of ab54291 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
competitive binding assays
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FormLiquid
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Additional notesThis product is an aliquot of membranes from Sf9 cells transfected with the human recombinant alpha 2a Adrenergic Receptor. The membranes will retain their original specific activity for several months when stored at -80 °C in the original packing solution.
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.
pH: 7.40
Constituents: 0.79% Tris HCl, 10% Glycerol, 1% BSAThis product is an active protein and may elicit a biological response in vivo, handle with caution.
General Info
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Alternative names
- ADA2A_HUMAN
- ADRA2
- ADRA2A
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FunctionAlpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is oxymetazoline > clonidine > epinephrine > norepinephrine > phenylephrine > dopamine > p-synephrine > p-tyramine > serotonin = p-octopamine. For antagonists, the rank order is yohimbine > phentolamine = mianserine > chlorpromazine = spiperone = prazosin > propanolol > alprenolol = pindolol.
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Sequence similaritiesBelongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRA2A sub-subfamily.
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Cellular localizationCell membrane.
- Information by UniProt
Datasheets and documents
References
ab54291 has not yet been referenced specifically in any publications.
