Recombinant human alpha 2a Adrenergic Receptor protein (ab54291)
Key features and details
- Expression system: Baculovirus infected Sf9 cells
- Active: Yes
- Suitable for: Competitive Binding Assays
Description
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Product name
Recombinant human alpha 2a Adrenergic Receptor protein
See all alpha 2a Adrenergic Receptor proteins and peptides -
Expression system
Baculovirus infected Sf9 cells -
Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Sequence
MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFG NVLVIIAVFT SRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGY WYFGKAWCEIYLALDVLFCTSS IVHLCAISLDRYWSITQAIEYNLKRT PRRIKAIIITVWVISAVISFPPLISIEKKGGGGG PQPAEPRCEINDQK WYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVA AP PGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALD LEESSSSD HAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGAT GIGTPAAGPGEERVGAAKAS RWRGRQNREKRFTFVLAVVIGVFVVCWF PFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSS LNPVIYTIFNHDFRRA FKKILCRGDRKRIV
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Associated products
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Related Products
Specifications
Our Abpromise guarantee covers the use of ab54291 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
Competitive Binding Assays
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Form
Liquid -
Additional notes
This product is an aliquot of membranes from Sf9 cells transfected with the human recombinant alpha 2a Adrenergic Receptor. The membranes will retain their original specific activity for several months when stored at -80 °C in the original packing solution. -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.
pH: 7.40
Constituents: 0.79% Tris HCl, 10% Glycerol, 1% BSAThis product is an active protein and may elicit a biological response in vivo, handle with caution.
General Info
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Alternative names
- ADA2A_HUMAN
- ADRA2
- ADRA2A
see all -
Function
Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is oxymetazoline > clonidine > epinephrine > norepinephrine > phenylephrine > dopamine > p-synephrine > p-tyramine > serotonin = p-octopamine. For antagonists, the rank order is yohimbine > phentolamine = mianserine > chlorpromazine = spiperone = prazosin > propanolol > alprenolol = pindolol. -
Sequence similarities
Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRA2A sub-subfamily. -
Cellular localization
Cell membrane. - Information by UniProt
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
References (0)
ab54291 has not yet been referenced specifically in any publications.