Product nameRecombinant Human alpha smooth muscle Actin protein
See all alpha smooth muscle Actin proteins and peptides
Protein lengthFull length protein
Amino Acid Sequence
SequenceMGSSHHHHHHSSGLVPRGSHMGSHMEEEDSTALVCDNGSGLCKAGFAGDD APRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGI ITNWDDMEKIWHHSFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFE TFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAI MRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFEN EMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIH ETTYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPSTM KIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDEAGPSIVHRKCF
Molecular weight44 kDa including tags
Amino acids3 to 377
TagsHis tag N-Terminus
- Anti-alpha smooth muscle Actin antibody [4A4] (ab119952)
- Anti-alpha smooth muscle Actin antibody (ab15734)
- Anti-6X His tag® antibody [HIS.H8] (ab18184)
- Anti-alpha smooth muscle Actin antibody (ab21027)
- Anti-6X His tag® antibody [4D11] (ab5000)
- Anti-alpha smooth muscle Actin antibody (ab5694)
- Anti-alpha smooth muscle Actin antibody [1A4] (ab7817)
- Anti-alpha smooth muscle Actin antibody [1A4] (FITC) (ab8211)
- Anti-6X His tag® antibody (ab9108)
Our Abpromise guarantee covers the use of ab134555 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Purity> 85 % SDS-PAGE.
ab134555 is purified using conventional chromatography techniques.
Concentration information loading...
Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Constituents: 0.32% Tris HCl, 10% Glycerol, 0.88% Sodium chloride
- a actin
FunctionActins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
Involvement in diseaseDefects in ACTA2 are the cause of aortic aneurysm familial thoracic type 6 (AAT6) [MIM:611788]. AATs are characterized by permanent dilation of the thoracic aorta usually due to degenerative changes in the aortic wall. They are primarily associated with a characteristic histologic appearance known as 'medial necrosis' or 'Erdheim cystic medial necrosis' in which there is degeneration and fragmentation of elastic fibers, loss of smooth muscle cells, and an accumulation of basophilic ground substance.
Sequence similaritiesBelongs to the actin family.
Cellular localizationCytoplasm > cytoskeleton.
- Information by UniProt
ab134555 has not yet been referenced specifically in any publications.