Overview

  • Product name

    Recombinant Human ANAPC2 protein
  • Protein length

    Protein fragment

Description

  • Nature

    Recombinant
  • Source

    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species

      Human
    • Molecular weight

      25 kDa
    • Amino acids

      604 to 820
    • Tags

      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab127267 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20ºC.

    Constituents: 0.32% Tris HCl, 0.58% Sodium chloride

  • Reconstitution
    Reconstitute with water to desired concentration.

General Info

  • Alternative names

    • anapc2
    • Anaphase promoting complex subunit 2
    • Anaphase-promoting complex subunit 2
    • ANC2_HUMAN
    • APC2
    • Cyclosome subunit 2
    • KIAA1406
    • OTTHUMP00000022692
    • RP11 350O14.5
    see all
  • Function

    Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
  • Pathway

    Protein modification; protein ubiquitination.
  • Sequence similarities

    Belongs to the cullin family.
  • Information by UniProt

References

ab127267 has not yet been referenced specifically in any publications.

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