Recombinant Human Angiopoietin 1 protein (denatured) (ab113163)

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Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
      Q15389
    • Species
      Human
    • Sequence
      MSNQRRSPENSGRRYNRIQHGQCAYTFILPEHDGNCRESTTDQYNTNALQ RDAPHVEPDFSSQKLQHLEHVMENYTQWLQKLENYIVENMKSEMAQIQQN AVQNHTATMLEIGTSLLSQTAEQTRKLTDVETQVLNQTSRLEIQLLENSL STYKLEKQLLQQTNEILKIHEKNSLLEHKILEMEGKHKEELDTLKEEKEN LQGLVTRQTYIIQELEKQLNRATTNNSVLQKQQLELMDTVHNLVNLCTKE GVLLKGGKREEEKPFRDCADVYQAGFNKSGIYTIYINNMPEPKKVFCNMD VNGGGWTVIQHREDGSLDFQRGWKEYKMGFGNPSGEYWLGNEFIFAITSQ RQYMLRIELMDWEGNRAYSQYDRFHIGNEKQNYRLYLKGHTGTAGKQSSL ILHGADFSTKDADNDNCMCKCALMLTGGWWFDACGPSNLNGMFYTAGQNH GKLNGIKWHYFKGPSYSLRSTTMMIRPLDF
    • Molecular weight
      56 kDa
    • Amino acids
      1 to 480

Specifications

Our Abpromise guarantee covers the use of ab113163 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity
    > 85 % SDS-PAGE.
    ab113163 is purified by using conventional chromatography techniques
  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 6.01% Urea, 5% Glycerol

General Info

  • Alternative names
    • AGP 1
    • AGP1
    • AGPT
    • ANG
    • ANG 1
    • ANG-1
    • ANG1
    • Angiopoietin-1
    • Angiopoietin1
    • ANGP1_HUMAN
    • ANGPT 1
    • Angpt1
    • KIAA0003
    • OTTHUMP00000227592
    • OTTHUMP00000227599
    • OTTHUMP00000227600
    see all
  • Function
    Binds and activates TIE2 receptor by inducing its tyrosine phosphorylation. Implicated in endothelial developmental processes later and distinct from that of VEGF. Appears to play a crucial role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. Mediates blood vessel maturation/stability. It may play an important role in the heart early development.
  • Sequence similarities
    Contains 1 fibrinogen C-terminal domain.
  • Post-translational
    modifications
    Glycosylated.
  • Cellular localization
    Secreted.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant Human Angiopoietin 1 protein (denatured) (ab113163)
    SDS-PAGE - Recombinant Human Angiopoietin 1 protein (denatured) (ab113163)
    ab113163 at 3 µg analysed by 15% SDS PAGE.

References

ab113163 has not yet been referenced specifically in any publications.

Publishing research using ab113163? Please let us know so that we can cite the reference in this datasheet.

Customer reviews and Q&As

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1 Review or Q&A

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send sequence alignment between human and mosue angiopoietin 1
send IHC-P protocol

Thank you for contacting us.

I have attached the results of the sequence alignment between mouse and human angiopoietin 1.

The link to our IHC-P protocol is as follows:
https://www.abcam.com/index.html?pageconfig=resource&...

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