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  1. Link

    recombinant-human-angiopoietin-1-protein-denatured-ab113163.pdf

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Cardiovascular Angiogenesis Growth Factors Angiopoietin
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Recombinant Human Angiopoietin 1 protein (denatured) (ab113163)

  • Datasheet
Submit a review Q&A (1)

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  • SDS-PAGE - Recombinant Human Angiopoietin 1 protein (denatured) (ab113163)
  • Datasheet
  • References
  • Protocols

Description

  • Product name

    Recombinant Human Angiopoietin 1 protein (denatured)
    See all Angiopoietin 1 proteins and peptides
  • Purity

    > 85 % SDS-PAGE.
    ab113163 is purified by using conventional chromatography techniques
  • Expression system

    Escherichia coli
  • Accession

    Q15389
  • Protein length

    Protein fragment
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      MSNQRRSPENSGRRYNRIQHGQCAYTFILPEHDGNCRESTTDQYNTNALQ RDAPHVEPDFSSQKLQHLEHVMENYTQWLQKLENYIVENMKSEMAQIQQN AVQNHTATMLEIGTSLLSQTAEQTRKLTDVETQVLNQTSRLEIQLLENSL STYKLEKQLLQQTNEILKIHEKNSLLEHKILEMEGKHKEELDTLKEEKEN LQGLVTRQTYIIQELEKQLNRATTNNSVLQKQQLELMDTVHNLVNLCTKE GVLLKGGKREEEKPFRDCADVYQAGFNKSGIYTIYINNMPEPKKVFCNMD VNGGGWTVIQHREDGSLDFQRGWKEYKMGFGNPSGEYWLGNEFIFAITSQ RQYMLRIELMDWEGNRAYSQYDRFHIGNEKQNYRLYLKGHTGTAGKQSSL ILHGADFSTKDADNDNCMCKCALMLTGGWWFDACGPSNLNGMFYTAGQNH GKLNGIKWHYFKGPSYSLRSTTMMIRPLDF
    • Predicted molecular weight

      56 kDa
    • Amino acids

      1 to 480
  • Description

    Recombinant Human Angiopoietin 1 protein

Associated products

  • Related Products

    • Anti-Angiopoietin 1 antibody [171718] (ab49694)

Specifications

Our Abpromise guarantee covers the use of ab113163 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 6.01% Urea, 5% Glycerol

General Info

  • Alternative names

    • AGP 1
    • AGP1
    • AGPT
    • ANG
    • ANG 1
    • ANG-1
    • ANG1
    • Angiopoietin-1
    • Angiopoietin1
    • ANGP1_HUMAN
    • ANGPT 1
    • Angpt1
    • KIAA0003
    • OTTHUMP00000227592
    • OTTHUMP00000227599
    • OTTHUMP00000227600
    see all
  • Function

    Binds and activates TIE2 receptor by inducing its tyrosine phosphorylation. Implicated in endothelial developmental processes later and distinct from that of VEGF. Appears to play a crucial role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. Mediates blood vessel maturation/stability. It may play an important role in the heart early development.
  • Sequence similarities

    Contains 1 fibrinogen C-terminal domain.
  • Post-translational
    modifications

    Glycosylated.
  • Cellular localization

    Secreted.
  • Target information above from: UniProt accession Q15389 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

Images

  • SDS-PAGE - Recombinant Human Angiopoietin 1 protein (denatured) (ab113163)
    SDS-PAGE - Recombinant Human Angiopoietin 1 protein (denatured) (ab113163)
    ab113163 at 3 µg analysed by 15% SDS PAGE.

Datasheets and documents

    • Datasheet
  • References

    ab113163 has not yet been referenced specifically in any publications.

    Publishing research using ab113163? Please let us know so that we can cite the reference in this datasheet.

    Customer reviews and Q&As

    Show All Reviews Q&A
    Submit a review Submit a question

    Question

    send sequence alignment between human and mosue angiopoietin 1
    send IHC-P protocol

    Read More

    Abcam community

    Verified customer

    Asked on Aug 21 2012

    Answer

    Thank you for contacting us.

    I have attached the results of the sequence alignment between mouse and human angiopoietin 1.

    The link to our IHC-P protocol is as follows:
    https://www.abcam.com/index.html?pageconfig=resource&rid=11384

    The file is also attached for your convenience.

    I hope this information is helpful to you. Please do not hesitate to contact us if you need any more advice or information.

    Use our products? Submit an Abreview. Earn rewards!
    https://www.abcam.com/abreviews

    Read More

    Abcam Scientific Support

    Answered on Aug 21 2012

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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