Description

  • Product name

    Recombinant Human Annexin A1/ANXA1 protein
    See all Annexin A1/ANXA1 proteins and peptides
  • Expression system

    Escherichia coli
  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Amino acids

      1 to 346

Specifications

Our Abpromise guarantee covers the use of ab92966 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    ELISA

    SDS-PAGE

    Mass Spectrometry

  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Preservative: 0.68% Imidazole
    Constituents: 0.0078% Beta mercaptoethanol, 0.316% Tris HCl, 2.9% Sodium chloride

General Info

  • Alternative names

    • Annexin 1
    • Annexin A1
    • Annexin I
    • Annexin I (lipocortin I)
    • Annexin-1
    • AnnexinA1
    • AnnexinI
    • ANX 1
    • ANX A1
    • ANX1
    • ANXA 1
    • ANXA1
    • ANXA1 protein
    • ANXA1_HUMAN
    • Calpactin 2
    • Calpactin II
    • Calpactin-2
    • CalpactinII
    • Chromobindin 9
    • Chromobindin-9
    • Chromobindin9
    • HGNC:533
    • Lipocortin 1
    • Lipocortin I
    • Lipocortin1
    • LipocortinI
    • LPC 1
    • LPC1
    • p35
    • Phospholipase A2 inhibitory protein
    see all
  • Function

    Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis. This protein regulates phospholipase A2 activity. It seems to bind from two to four calcium ions with high affinity.
  • Sequence similarities

    Belongs to the annexin family.
    Contains 4 annexin repeats.
  • Domain

    A pair of annexin repeats may form one binding site for calcium and phospholipid.
  • Post-translational
    modifications

    Phosphorylated by protein kinase C, epidermal growth factor receptor/kinase and TRPM7. Phosphorylation results in loss of the inhibitory activity.
  • Cellular localization

    Nucleus. Cytoplasm. Cell projection > cilium. Basolateral cell membrane. Found in the cilium, nucleus and basolateral cell membrane of ciliated cells in the tracheal endothelium (By similarity). Found in the cytoplasm of type II pneumocytes and alveolar macrophages.
  • Information by UniProt

Images

  • 12% SDS-PAGE showing ab92966
    Lane 1 MWM
    Lane 2 Stained with Coomassie Blue
    Lane 3 Peptide fingerprinting by MALDI-TOF-TOF mass spectrometry

References

ab92966 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab92966.
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