- Datasheet
- Specific References
- Protocols
Overview
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Product nameRecombinant Human Apc1 protein
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Protein lengthProtein fragment
Description
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NatureRecombinant
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SourceWheat germ
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Amino Acid Sequence
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SpeciesHuman
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SequenceNSEFLPVVKCTIDNTLDQWLQVGGDMCVHAYLSGQPLEESQLSMLACFLV YHSVPAPQHLPPIGLEGSTSFAELLFKFKQLKMPVRALLRLAPLLLGNPQ PMVM
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Amino acids1841 to 1944
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Tagsproprietary tag N-Terminus
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Specifications
Our Abpromise guarantee covers the use of ab163855 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
Western blot
ELISA
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FormLiquid
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Additional notesProtein concentration is above or equal to 0.05 mg/ml.
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00
Constituents: 0.31% Glutathione, 0.79% Tris HCl
General Info
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Alternative names
- ANAPC 1
- Anapc1
- Anaphase promoting complex subunit 1
see all -
FunctionComponent of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
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PathwayProtein modification; protein ubiquitination.
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Sequence similaritiesBelongs to the APC1 family.
Contains 4 PC repeats. -
Post-translational
modificationsPhosphorylated. Phosphorylation on Ser-355 occurs specifically during mitosis. - Information by UniProt
Images
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SDS-PAGE - Recombinant Human Apc1 protein (ab163855)ab163855 on a 12.5% SDS-PAGE stained with Coomassie Blue.
References
ab163855 has not yet been referenced specifically in any publications.
Customer reviews and Q&As
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"