Description

  • Product name

    Recombinant Human APIP protein
  • Purity

    > 85 % SDS-PAGE.
    ab128440 is purified using conventional chromatography techniques
  • Expression system

    Escherichia coli
  • Accession

  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      MGSSHHHHHH SSGLVPRGSH MGSHMSGCDA REGDCCSRRC GAQDKEHPRY LIPELCKQFY HLGWVTGTGG GISLKHGDEI YIAPSGVQKE RIQPEDMFVC DINEKDISGP SPSKKLKKSQ CTPLFMNAYT MRGAGAVIHT HSKAAVMATL LFPGREFKIT HQEMIKGIKK CTSGGYYRYD DMLVVPIIEN TPEEKDLKDR MAHAMNEYPD SCAVLVRRHG VYVWGETWEK AKTMCECYDY LFDIAVSMKK VGLDPSQLPV GENGIV
    • Predicted molecular weight

      30 kDa including tags
    • Amino acids

      1 to 242
    • Tags

      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab128440 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Mass Spectrometry

  • Mass spectrometry

    MALDI-TOF
  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.02% DTT, 0.32% Tris HCl, 20% Glycerol

General Info

  • Alternative names

    • Apaf1 Interacting Protein
    • APAF1-interacting protein
    • APIP
    • APIP2
    • CG129
    • CGI 29
    • CGI29
    • dJ179L10.2
    • MMRP19
    • Monocyte/macrophage protein 19
    • MTNB_HUMAN
    • MTRu 1 P dehydratase
    • MTRu-1-P dehydratase
    • Probable methylthioribulose 1 phosphate dehydratase
    • Probable methylthioribulose-1-phosphate dehydratase
    see all
  • Function

    Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Has an anti-apoptotic function and prevents muscle ischemic damage. Inhibits the cytochrome c-dependent and APAF1-mediated cell death.
  • Tissue specificity

    Ubiquitously expressed with high expression in skeletal muscle, heart and kidney.
  • Pathway

    Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 2/6.
  • Sequence similarities

    Belongs to the aldolase class II family. MtnB subfamily.
  • Cellular localization

    Cytoplasm.
  • Information by UniProt

Images

  • 15% SDS-PAGE showing ab128440 (3 µg).

References

ab128440 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab128440.
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