Description

  • Product name

    Recombinant Human APLP2 protein
  • Expression system

    Wheat germ
  • Accession

  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      MAATGTAAAAATGRLLLLLLVGLTAPALALAGYIEALAANAGTGFAVAEP QIAMFCGKLNMHVNIQTGKWEPDPTGTKSCFETKEEVLQYCQEMYPELQI TNVMEANQRVSIDNWCRRDKKQCKSRFVTPFKCLVPPTPLPTNDVDVYFE TSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAKNLPKAERQT LIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRMALENYLAAL QSDPPRPHRILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQV MTHLHVIEERRNQTLSLLYKVPYVAQEIQEEIDELLQEQRADMDQFTASI SETPVDVRVSSEESEEIPPFHPFHPFPALPENEGSGVGEQDGGLIGAEEK VINSKNKVDENMVIDETLDVKEMIFNAERVGGLEEERESVGPLREDFSLS SSALIGLLVIAVAIATVIVISLVMLRKRQYGTISHGIVEVDPMLTPEERH LNKMQNHGYENPTYKYLEQMQI
    • Predicted molecular weight

      83 kDa including tags
    • Amino acids

      1 to 522

Specifications

Our Abpromise guarantee covers the use of ab114600 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    SDS-PAGE

    Western blot

  • Form

    Liquid
  • Additional notes

    Protein concentration is above or equal to 0.05 mg/ml.
    Best used within three months from the date of receipt.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names

    • amyloid beta (A4) precursor like protein 2
    • Amyloid like protein 2
    • Amyloid precursor protein homolog HSD 2
    • amyloid precursor protein homolog HSD2
    • Amyloid protein homolog
    • Amyloid-like protein 2
    • APLP-2
    • Aplp2
    • APLP2_HUMAN
    • APPH
    • APPL2
    • CDEBP
    • CDEI box binding protein
    • CDEI box-binding protein
    see all
  • Function

    May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein.
  • Tissue specificity

    Expressed in placenta, brain, heart, lung, liver, kidney and endothelial tissues.
  • Sequence similarities

    Belongs to the APP family.
    Contains 1 BPTI/Kunitz inhibitor domain.
  • Post-translational
    modifications

    The BPTI/Kunitz inhibitor domain is O-glycosylated.
  • Cellular localization

    Cell membrane. Nucleus.
  • Information by UniProt

Images

  • ab114600 analysed on a 12.5% SDS-PAGE gel stained with Coomassie Blue.

References

ab114600 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

Question
Answer

Thank you very much for your interest in ab114600.

As ab114600 has not been tested in afunctional assay. Therefore, I can offer a discount off a future purchase if you buy ab114600 now, test it in a functional assay and submit feedback to us in the form of an Abreview. It doesn’t matter whether the Abreview is positive or negative, we would just really like to receive your feedback. The discount would be to the value of 1 free PROTEIN.

If you are interested in this offer, please follow these steps:

1. Reply to this e-mail to let me know that you would like to proceed and test ab114600 in a functional assay. I will then send a discount code. This code must be issued before purchasing ab114600 so please wait for my reply before ordering.

2. Purchase ab114600 either by phone, fax, or online (www.abcam.com).

3. Test it in a functional assay.

4. Let us know the results, positive or negative, using our Abreview system (this will take about 10 minutes and images are great if you have them!). To find out how to submit an Abreview, please visit: https://www.abcam.com/abreviews.

5. After the review is submitted to us, the discount code becomes active. Simply place your new order by phone, fax, or on the web and mention the discount code. The discount can be redeemed for any PROTEIN ordered and the discount code is valid for 4 months after issue.

We are always pleased to obtain feedback about our products and any information is greatly appreciated! Even if ab114600 turns out to be unsuitable for a functional assay, you will still receive the discount on your next purchase after your Abreview has been submitted.

Please let me know if you have any questions about this offer and I would be happy to help you further.

The Terms and Conditions of this offer can be found at: www.abcam.com/collaborationdiscount.

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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