Overview

Description

  • Nature
    Recombinant
  • Source
    Yeast
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      AVLTQKQKKQ HSVLHLVPIN ATSKDDSDVT EVMWQPALRR GRGLQAQGYG VRIQDAGVYL LYSQVLFQDV TFTMGQVVSR EGQGRQETLF RCIRSMPSHP DRAYNSCYSA GVFHLHQGDI LSVIIPRARA KLNLSPHGTF LGFVKL
    • Molecular weight
      16 kDa
    • Amino acids
      105 to 250

Specifications

Our Abpromise guarantee covers the use of ab177588 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form
    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon reconsitution add a carrier protein (0.1% BSA). Store at -20°C. Working aliquots stored with a carrier protein are stable for at least 3 months at -20°C to -80°C..

General Info

  • Alternative names
    • A proliferation inducing ligand
    • A proliferation-inducing ligand
    • APRIL
    • CD256
    • TALL-2
    • TALL2
    • TNF related death ligand
    • TNF- and APOL-related leukocyte expressed ligand 2
    • TNF-related death ligand 1
    • TNF13_HUMAN
    • TNFSF13
    • TRDL-1
    • TRDL1
    • Tumor necrosis factor (ligand) superfamily, member 13
    • Tumor necrosis factor ligand superfamily member 13
    • Tumor necrosis factor like protein ZTNF2
    • Tumor necrosis factor related death ligand 1
    • UNQ383/PRO715
    • ZTNF2
    see all
  • Function
    Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA. May be implicated in the regulation of tumor cell growth. May be involved in monocyte/macrophage-mediated immunological processes.
  • Tissue specificity
    Expressed at high levels in transformed cell lines, cancers of colon, thyroid, lymphoid tissues and specifically expressed in monocytes and macrophages.
  • Sequence similarities
    Belongs to the tumor necrosis factor family.
  • Post-translational
    modifications
    The precursor is cleaved by furin.
  • Cellular localization
    Secreted.
  • Information by UniProt

References

ab177588 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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