Overview

  • Product name

    Recombinant Human ARHGAP20 protein
  • Protein length

    Protein fragment

Description

  • Nature

    Recombinant
  • Source

    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species

      Human
    • Molecular weight

      22 kDa
    • Amino acids

      526 to 729
    • Tags

      His-DHFR tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab127315 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20ºC.

    Constituents: 0.32% Tris HCl, 0.58% Sodium chloride

  • Reconstitution
    Reconstitute with water to desired concentration

General Info

  • Alternative names

    • Arhgap20
    • KIAA1391
    • RARHOGAP
    • RHG20_HUMAN
    • Rho GTPase activating protein 20
    • Rho GTPase-activating protein 20
    • Rho type GTPase activating protein 20
    • Rho-type GTPase-activating protein 20
    see all
  • Function

    GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.
  • Tissue specificity

    Expressed predominantly in the brain. Lower expression is found in lymph nodes.
  • Involvement in disease

    Note=A chromosomal aberration involving ARHGAP20 may be a cause of B-cell chronic lymphocytic leukemia (B-CLL). Translocation t(X;11)(q21;q23) with BRWD3 does not result in fusion transcripts but disrupts both genes.
  • Sequence similarities

    Contains 1 PH domain.
    Contains 1 Ras-associating domain.
    Contains 1 Rho-GAP domain.
  • Developmental stage

    Low expression is found in fetal liver.
  • Information by UniProt

References

ab127315 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab127315.
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