Overview

  • Product name

    Recombinant Human ASC-2/NRC protein
  • Protein length

    Protein fragment

Description

  • Nature

    Recombinant
  • Source

    Wheat germ
  • Amino Acid Sequence
    • Species

      Human
    • Sequence

      VGSHPELLPSIAPSQNLVSKETSTTALQASVARPELEVNAAIVSGQSSEP KEIVEKSKIPGRRNSRTEEPTVASESVENGHRKRSSRPASASSSTKDITS AVQSKRRKSK
    • Amino acids

      1954 to 2063
    • Tags

      GST tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab161520 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    Western blot

  • Form

    Liquid
  • Additional notes

    Protein concentration is above or equal to 0.05 mg/ml.

     This product was previously labelled as ASC-2

     

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names

    • Activating signal cointegrator 2
    • AIB3
    • Amplified in breast cancer 3 protein
    • Cancer amplified transcriptional coactivator ASC 2
    • NCOA6
    • Nuclear receptor coactivator 6
    • Nuclear receptor coactivator RAP250
    • PPAR interacting protein
    • Thyroid hormone receptor binding protein
    see all
  • Relevance

    The protein encoded by this gene is a nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone dependent fashion. It is involved in the coactivation of different nuclear receptors, such as steroids (GR and ERs), retinoids (RARs and RXRs), thyroid hormone (TRs), vitamin D3 (VDR) and prostanoids (PPARs). It probably functions as a general coactivator, rather than just a nuclear receptor coactivator,and may also be involved in the coactivation of the NFkB pathway (referenced from swissprot).
  • Cellular localization

    Nuclear

Images

  • ab161520 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab161520 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab161520.
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