Overview

Description

  • Nature

    Recombinant
  • Source

    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species

      Human
    • Sequence

      MGSSHHHHHH SSGLVPRGSH MGSQSEGHRG AQLQAELRSL KEAFSNFSSS TLTEVQAIST HGGSVGDKIT SLGAKLEKQQ QDLKADHDAL LFHLKHFPVD LRFVACQMEL LHSNGSQRTC CPVNWVEHQG SCYWFSHSGK AWAEAEKYCQ LENAHLVVIN SWEEQKFIVQ HTNPFNTWIG LTDSDGSWKW VDGTDYRHNY KNWAVTQPDN WHGHELGGSE DCVEVQPDGR WNDDFCLQVY RWVCEKRRNA TGEVA
    • Molecular weight

      29 kDa including tags
    • Amino acids

      80 to 311
    • Tags

      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab134625 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Mass Spectrometry

    SDS-PAGE

  • Mass spectrometry

    MALDI-TOF
  • Purity

    > 90 % SDS-PAGE.
    ab134625 was purified using conventional chromatography techniques.
  • Form

    Liquid
  • Additional notes

    Previously labelled as Asialoglycoprotein Receptor 2.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.02% DTT, 0.32% Tris HCl, 30% Glycerol, 1.17% Sodium chloride

General Info

  • Alternative names

    • ASGP R
    • ASGP-R 2
    • ASGPR 2
    • ASGPR2
    • Asgr2
    • ASGR2_HUMAN
    • Asialoglycoprotein receptor 2
    • C type lectin domain family 4 member H2
    • C-type lectin domain family 4 member H2
    • CLEC4H2
    • HBxAg-binding protein
    • HBXBP
    • Hepatic lectin 2
    • Hepatic lectin H2
    • Hepatic lectin R2/3
    • HL-2
    • Hs.1259
    • L H2
    • LH2
    • MGC108546
    • MHL 2
    • RHL2
    see all
  • Function

    Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface.
  • Tissue specificity

    Expressed exclusively in hepatic parenchymal cells.
  • Sequence similarities

    Contains 1 C-type lectin domain.
  • Cellular localization

    Membrane.
  • Information by UniProt

Images

  • 15% SDS-PAGE analysis of ab134625 (3ug)

References

ab134625 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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