Recombinant Human Asialoglycoprotein Receptor 1/HL-1 (ab151893)

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Description

  • Product name

    Recombinant Human Asialoglycoprotein Receptor 1/HL-1
    See all Asialoglycoprotein Receptor 1/HL-1 proteins and peptides

  • Purity

    > 95 % SDS-PAGE.
    ab151893 is greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Lyophilized from a 0.2 µM filtered solution.

  • Endotoxin level

    < 0.100 Eu/µg

  • Expression system

    HEK 293 cells

  • Accession

    P07306

  • Protein length

    Protein fragment

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      QNSQLQEELRGLRETFSNFTASTEAQVKGLSTQGGNVGRKMKSLESQLEK QQKDLSEDHSSLLLHVKQFVSDLRSLSCQMAALQGNGSERTCCPVNWVEH ERSCYWFSRSGKAWADADNYCRLEDAHLVVVTSWEEQKFVQHHIGPVNTW MGLHDQNGPWKWVDGTDYETGFKNWRPEQPDDWYGHGLGGGEDCAHFTDD GRWNDDVCQRPYRWVCETELDKASQEPPLLVDHHHHHH

    • Predicted molecular weight

      27 kDa including tags

    • Amino acids

      62 to 291

    • Tags

      His tag C-Terminus

Specifications

Our Abpromise guarantee covers the use of ab151893 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    HPLC

  • Form

    Lyophilised

  • Additional notes

    Previously labelled as Asialoglycoprotein Receptor 1. 

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -80°C.

    pH: 7.20
    Constituents: 99% Phosphate Buffer, 0.88% Sodium chloride

  • Reconstitution
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

General Info

  • Alternative names

    • ASGP-R 1
    • ASGPR
    • ASGPR 1
    • ASGPR1
    • Asgr1
    • ASGR1_HUMAN
    • Asialoglycoprotein receptor 1
    • C type lectin domain family 4 member H1
    • C-type lectin domain family 4 member H1
    • CLEC4H1
    • Hepatic lectin H1
    • HL-1
    see all

  • Function

    Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface.

  • Tissue specificity

    Expressed exclusively in hepatic parenchymal cells.

  • Sequence similarities

    Contains 1 C-type lectin domain.

  • Post-translational
    modifications

    Phosphorylated on a cytoplasmic Ser residue.

  • Cellular localization

    Membrane.
  • Information by UniProt

References

ab151893 has not yet been referenced specifically in any publications.

Publishing research using ab151893? Please let us know so that we can cite the reference in this datasheet.

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