Product nameRecombinant human ASK1 protein
See all ASK1 proteins and peptides
Protein lengthProtein fragment
SourceBaculovirus infected Sf9 cells
Amino Acid Sequence
Amino acids649 to 946
TagsGST tag N-Terminus
Our Abpromise guarantee covers the use of ab60325 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Purity> 90 % SDS-PAGE.
Purity: >90% as determined by densitometry.
ab43614 (Human Myelin Basic Protein full length protein) can be utilized as a substrate for assessing Kinase activity
Concentration information loading...
Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Constituents: 0.0038% EGTA, 0.00174% PMSF, 0.00385% DTT, 0.79% Tris HCl, 0.00292% EDTA, 25% Glycerol, 0.87% Sodium chloride
This product is an active protein and may elicit a biological response in vivo, handle with caution.
- Apoptosis signal regulating kinase 1
- Apoptosis signal-regulating kinase 1
- ASK 1
FunctionComponent of a protein kinase signal transduction cascade. Phosphorylates and activates MAP2K4 and MAP2K6, which in turn activate the JNK and p38 MAP kinases, respectively. Overexpression induces apoptotic cell death.
Tissue specificityAbundantly expressed in heart and pancreas.
Sequence similaritiesBelongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
Contains 1 protein kinase domain.
modificationsDephosphorylated and activated by PGAM5.
- Information by UniProt
ab60325 has not yet been referenced specifically in any publications.