Description

  • Product name

    Recombinant Human ATG4D protein
  • Expression system

    Wheat germ
  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      MGGKPRHSLYFIGYQDDFLLYLDPHYCQPTVDVSQADFPLESFHCTSPRK MAFAKMDPSCTVGFYAGDRKEFETLCSELTRVLSSSSATERYPMFTLAEG HAQDHSLDDLCSQLAQPTLRLPRTGRLLRAKRPSSEDFVFL
    • Amino acids

      1 to 141
    • Tags

      GST tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab164720 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    Western blot

  • Form

    Liquid
  • Additional notes

    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names

    • 9830134P12Rik
    • APG4 autophagy 4 homolog D
    • APG4 D
    • APG4, S. cerevisiae, homolog of, D
    • APG4D
    • ATG4 autophagy related 4 homolog D (S. cerevisiae)
    • Atg4d
    • ATG4D_HUMAN
    • Atg4dl
    • AUT like 4 cysteine endopeptidase
    • AUT-like 4 cysteine endopeptidase
    • AUTL4
    • Autophagin 4
    • Autophagin-4
    • autophagy 4, S. cerevisiae, homolog of, D
    • autophagy related 4D, cysteine peptidase
    • Autophagy related cysteine endopeptidase 4
    • Autophagy related protein 4 homolog D
    • Autophagy-related cysteine endopeptidase 4
    • Autophagy-related protein 4 homolog D
    • Cysteine protease ATG4D
    • Cysteine protease involved in autophagy
    • MGC31226
    see all
  • Function

    Cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes.
  • Tissue specificity

    Mainly expressed in skeletal muscle and, to a lower extent, in testis.
  • Sequence similarities

    Belongs to the peptidase C54 family.
  • Cellular localization

    Cytoplasm.
  • Information by UniProt

Images

  • ab164720 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab164720 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab164720.
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