Recombinant Human Axl protein (ab152219)

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SDS-PAGE - Recombinant Human Axl protein (ab152219)

    Key features and details

    • Expression system: Wheat germ
    • Tags: GST tag N-Terminus
    • Suitable for: ELISA, WB, SDS-PAGE

    Description

    • Product name

      Recombinant Human Axl protein
      See all Axl proteins and peptides

    • Expression system

      Wheat germ

    • Accession

      P30530

    • Protein length

      Full length protein

    • Animal free

      No

    • Nature

      Recombinant

      • Species

        Human

      • Sequence

        MAWRCPRMGRVPLAWCLALCGWACMAPRGTQAEESPFVGNPGNITGARGL TGTLRCQLQVQGEPPEVHWLRDGQILELADSTQTQVPLGEDEQDDWIVVS QLRITSLQLSDTGQYQCLVFLGHQTFVSQPGYVGLEGLPYFLEEPEDRTV AANTPFNLSCQAQGPPEPVDLLWLQDAVPLATAPGHGPQRSLHVPGLNKT SSFSCEAHNAKGVTTSRTATITVLPQQPRNLHLVSRQPTELEVAWTPGLS GIYPLTHCTLQAVLSDDGMGIQAGEPDPPEEPLTSQASVPPHQLRLGSLH PHTPYHIRVACTSSQGPSSWTHWLPVETPEGVPLGPPENISATRNGSQAF VHWQEPRAPLQGTLLGYRLAYQGQDTPEVLMDIGLRQEVTLELQGDGSVS NLTVCVAAYTAAGDGPWSLPVPLEAWRPGQAQPVHQLVKEPSTPAFSWPW WYVLLGAVVAAACVLILALFLVHRRKKETRYGEVFEPTVERGELVVRYRV RKSYSRRTTEATLNSLGISEELKEKLRDVMVDRHKVALGKTLGEGEFGAV MEGQLNQDDSILKVAVKTMKIAICTRSELEDFLSEAVCMKEFDHPNVMRL IGVCFQGSERESFPAPVVILPFMKHGDLHSFLLYSRLGDQPVYLPTQMLV KFMADIASGMEYLSTKRFIHRDLAARNCMLNENMSVCVADFGLSKKIYNG DYYRQGRIAKMPVKWIAIESLADRVYTSKSDVWSFGVTMWEIATRGQTPY PGVENSEIYDYLRRGNRLKQPADCLDGLYALMSRCWELNPQDRPSFTELR EDLENTLKALPPAQEPDEILYVNMDEGGGYPEPPGAAGGADPPTQPDPKD SCSCLTAAEVHPAGRYVLCPSTTPSPAQPADRGSPAAPGQEDGA

      • Predicted molecular weight

        125 kDa including tags

      • Amino acids

        1 to 894

      • Tags

        GST tag N-Terminus

    Specifications

    Our Abpromise guarantee covers the use of ab152219 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      ELISA

      Western blot

      SDS-PAGE

    • Form

      Liquid

    • Additional notes

       

       

    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

      pH: 8.00
      Constituents: 0.31% Glutathione, 0.79% Tris HCl

    General Info

    • Alternative names

      • Adhesion related kinase
      • AI323647
      • Ark
      • Axl
      • AXL oncogene
      • AXL receptor tyrosine kinase
      • AXL transforming gene
      • AXL transforming sequence/gene
      • EC 2.7.10.1
      • JTK11
      • Oncogene AXL
      • Tyro7
      • Tyrosine protein kinase receptor UFO
      • Tyrosine-protein kinase receptor UFO
      • UFO
      • UFO_HUMAN
      see all

    • Function

      May function as a signal transducer between specific cell types of mesodermal origin. In case of filovirus infection, seems to function as a cell entry factor.

    • Tissue specificity

      Highly expressed in metastatic colon tumors. Expressed in primary colon tumors. Weakly expressed in normal colon tissue.

    • Sequence similarities

      Belongs to the protein kinase superfamily. Tyr protein kinase family. AXL/UFO subfamily.
      Contains 2 fibronectin type-III domains.
      Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
      Contains 1 protein kinase domain.

    • Cellular localization

      Membrane.
    • Information by UniProt

    Images

    • SDS-PAGE - Recombinant Human Axl protein (ab152219)
      SDS-PAGE - Recombinant Human Axl protein (ab152219)
      12.5% SDS-PAGE analysis of ab152219 stained with Coomassie Blue.

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    References (0)

    Publishing research using ab152219? Please let us know so that we can cite the reference in this datasheet.

    ab152219 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

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    Blocking experiment (IHC)

     Excellent
    Abreviews
    abreview image
    Application
    Immunohistochemistry (PFA fixed)
    Recombinant human Axl protein was used in a blocking experiment to validate antibody cat. #ab227871 for immunohistochemistry on PFA-fixed rat spinal cord slices.

    Abcam user community

    Verified customer

    Submitted Mar 15 2020

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