Product nameRecombinant Human beta 2 Microglobulin protein
See all beta 2 Microglobulin proteins and peptides
Protein lengthFull length protein
Amino Acid Sequence
SequenceMGSSHHHHHH SSGLVPRGSH MIQRTPKIQV YSRHPAENGK SNFLNCYVSG FHPSDIEVDL LKNGERIEKV EHSDLSFSKD WSFYLLYYTE FTPTEKDEYA CRVNHVTLSQ PKIVKWDRDM
Molecular weight14 kDa including tags
Amino acids21 to 119
TagsHis tag N-Terminus
- Anti-6X His tag® antibody [HIS.H8] (ab18184)
- Anti-beta 2 Microglobulin antibody [B2M-01] (Biotin) (ab21899)
- Anti-beta 2 Microglobulin antibody (ab31137)
- Anti-6X His tag® antibody [4D11] (ab5000)
- Anti-beta 2 Microglobulin antibody (ab54810)
- Anti-beta 2 Microglobulin antibody (ab6608)
- Anti-beta 2 Microglobulin antibody [EP2978Y] (ab75853)
- Anti-beta 2 Microglobulin antibody [B2M-01] (ab759)
Our Abpromise guarantee covers the use of ab98116 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Purity> 95 % SDS-PAGE.
ab98116 is purified by using conventional chromatography techniques.
Concentration information loading...
Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Constituents: 0.0308% DTT, 0.316% Tris HCl, 20% Glycerol, 0.58% Sodium chloride
- Beta 2 microglobin
FunctionComponent of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.
Involvement in diseaseDefects in B2M are the cause of hypercatabolic hypoproteinemia (HYCATHYP) [MIM:241600]. Affected individuals show marked reduction in serum concentrations of immunoglobulin and albumin, probably due to rapid degradation.
Note=Beta-2-microglobulin may adopt the fibrillar configuration of amyloid in certain pathologic states. The capacity to assemble into amyloid fibrils is concentration dependent. Persistently high beta(2)-microglobulin serum levels lead to amyloidosis in patients on long-term hemodialysis.
Sequence similaritiesBelongs to the beta-2-microglobulin family.
Contains 1 Ig-like C1-type (immunoglobulin-like) domain.
modificationsGlycation of Ile-21 is observed in long-term hemodialysis patients.
Cellular localizationSecreted. Detected in serum and urine.
- Information by UniProt
ab98116 has not yet been referenced specifically in any publications.