Bioactive grade

Recombinant human beta Defensin 1 protein (Active) (ab243114)

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Description

  • Product name

    Recombinant human beta Defensin 1 protein (Active)
    See all beta Defensin 1 proteins and peptides

  • Biological activity

    Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using CD34+ dendritic cells is in a concentration range of 100.0-1000.0 ng/ml.

  • Purity

    > 98 % SDS-PAGE.
    > 98 % by HPLC.

  • Endotoxin level

    < 1.000 Eu/µg

  • Expression system

    Escherichia coli

  • Accession

    P60022

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      GNFLTGLGHRSDHYNCVSSGGQCLYSACPIFTKIQGTCYRGKAKCCK

    • Predicted molecular weight

      5 kDa

    • Amino acids

      22 to 68

    • Additional sequence information

      This product includes the mature full length protein from aa 33 to 68 and the propeptide aa 22 to 32. The signal peptide is not included.

Specifications

Our Abpromise guarantee covers the use of ab243114 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Functional Studies

    SDS-PAGE

    HPLC

  • Form

    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 7.40
    Constituents: Phosphate Buffer, 0.75% Sodium chloride

    0.2 µm filtered.

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • Reconstitution
    Briefly centrifuge prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at -20 °C or below. Further dilutions should be made in appropriate buffered solutions.

General Info

  • Alternative names

    • BD 1
    • BD-1
    • BD1
    • beta 1
    • Beta defensin 1
    • Beta-defensin 1
    • DEFB 1
    • DEFB1
    • DEFB1_HUMAN
    • DEFB101
    • Defensin
    • Defensin beta 1
    • Defensin beta 1 preproprotein
    • HBD 1
    • hBD-1
    • HBD1
    • MGC51822
    see all

  • Function

    Has bactericidal activity.

  • Tissue specificity

    Plasma.

  • Sequence similarities

    Belongs to the beta-defensin family.

  • Cellular localization

    Secreted.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant human beta Defensin 1 protein (Active) (ab243114)
    SDS-PAGE - Recombinant human beta Defensin 1 protein (Active) (ab243114)
    SDS Page analysis of ab243114

References

ab243114 has not yet been referenced specifically in any publications.

Publishing research using ab243114? Please let us know so that we can cite the reference in this datasheet.

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