Biogenesis of lysosome-related organelles complex 1 subunit 2
BLOC-1 subunit 2
May play a role in cell proliferation. The BLOC-1 complex is required for normal biogenesis of lysosome-related organelles, such as platelet dense granules and melanosomes. Plays a role in intracellular vesicle trafficking.
Isoform 1 and isoform 2 are widely expressed. Expressed in various malignant tumor tissues (at protein level).
Belongs to the BLOC1S2 family.
Cytoplasm > cytoskeleton > centrosome. Localizes to the centrosomes in a microtubule-dependent manner.