Recombinant Human Blood Group Antigen Precursor protein (ab113153)

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Overview

  • Product name
    Recombinant Human Blood Group Antigen Precursor protein
  • Protein length
    Full length protein

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
      P16442
    • Species
      Human
    • Molecular weight
      37 kDa
    • Amino acids
      54 to 354
    • Tags
      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab113153 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Mass Spectrometry

  • Mass spectrometry
    MALDI-TOF
  • Purity
    > 85 % SDS-PAGE.
    ab113153 was purified using conventional chromatography techniques.
  • Form
    Liquid
  • Additional notes


  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 0.04% DTT, 20% Glycerol, 1.17% Sodium chloride

General Info

  • Alternative names
    • A transferase
    • A3GALNT
    • A3GALT1
    • Abo
    • ABO A3 transferase
    • ABO blood group (transferase A alpha 1-3 N acetylgalactosaminyltransferase transferase B alpha 1 3 galactosyltransferase)
    • ABO glycosyltransferase
    • ABO weak transfer
    • B (A) alpha 1, 3 glactosyltransferase
    • B transferase
    • BGAT_HUMAN
    • Fucosylglycoprotein 3 alpha galactosyltransferase
    • Fucosylglycoprotein 3-alpha-galactosyltransferase
    • Fucosylglycoprotein alpha N acetylgalactosaminyltransferase
    • Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase
    • Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase soluble form
    • Glycoprotein fucosylgalactoside alpha galactosyltransferase
    • Glycoprotein fucosylgalactoside alpha N acetylgalactosaminyltransferase
    • Glycoprotein-fucosylgalactoside alpha-galactosyltransferase
    • Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase
    • GTB
    • Histo blood group A transferase
    • Histo blood group A2 transferase
    • Histo blood group ABO system transferase
    • Histo blood group B transferase
    • Histo-blood group A transferase
    • Histo-blood group B transferase
    • NAGAT
    see all
  • Function
    This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity.
  • Pathway
    Protein modification; protein glycosylation.
  • Sequence similarities
    Belongs to the glycosyltransferase 6 family.
  • Domain
    The conserved DXD motif is involved in cofactor binding. The manganese ion interacts with the beta-phosphate group of UDP and may also have a role in catalysis.
  • Post-translational
    modifications
    The soluble form derives from the membrane form by proteolytic processing.
  • Cellular localization
    Golgi apparatus > Golgi stack membrane. Secreted. Membrane-bound form in trans cisternae of Golgi. Secreted into the body fluid.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant Human Blood Group Antigen Precursor protein (ab113153)
    SDS-PAGE - Recombinant Human Blood Group Antigen Precursor protein (ab113153)
    15% SDS-PAGE showing ab113153 (3 µg) at approximately 37.4 kDa

References

ab113153 has not yet been referenced specifically in any publications.

Publishing research using ab113153? Please let us know so that we can cite the reference in this datasheet.

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