Recombinant Human BMP15 protein (ab127067)

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Key features and details

  • Expression system: Escherichia coli
  • Suitable for: SDS-PAGE

Description

  • Product name

    Recombinant Human BMP15 protein

  • Expression system

    Escherichia coli

  • Accession

    O95972

  • Protein length

    Protein fragment

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Predicted molecular weight

      29 kDa

    • Amino acids

      137 to 387

Specifications

Our Abpromise guarantee covers the use of ab127067 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Lyophilized
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20ºC.

    Constituents: 0.32% Tris HCl, 0.58% Sodium chloride

  • Reconstitution
    Reconstitute with water to desired concentration.

General Info

  • Alternative names

    • BMP 15
    • BMP-15
    • BMP15
    • BMP15_HUMAN
    • Bone morphogenetic protein 15
    • GDF 9B
    • GDF-9B
    • GDF9B
    • Growth/differentiation factor 9B
    • ODG2
    • POF4
    see all

  • Function

    May be involved in follicular development. Oocyte-specific growth/differentiation factor that stimulates folliculogenesis and granulosa cell (GC) growth.

  • Involvement in disease

    Defects in BMP15 are the cause of ovarian dysgenesis type 2 (ODG2) [MIM:300510]; also known as X-linked hypergonadotropic ovarian dysgenesis or hypergonadotropic ovarian failure due to ovarian dysgenesis. Ovarian dysgenesis leads to ovarian failure and accounts for about half of the cases of primary amenorrhea.
    Defects in BMP15 are the cause of premature ovarian failure type 4 (POF4) [MIM:300510]. An ovarian disorder defined as the cessation of ovarian function under the age of 40 years. It is characterized by oligomenorrhea or amenorrhea, in the presence of elevated levels of serum gonadotropins and low estradiol.

  • Sequence similarities

    Belongs to the TGF-beta family.

  • Cellular localization

    Secreted.
  • Information by UniProt

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

References (0)

Publishing research using ab127067? Please let us know so that we can cite the reference in this datasheet.

ab127067 has not yet been referenced specifically in any publications.

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