Recombinant Human BNP protein (ab87200)

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Description

  • Product name

    Recombinant Human BNP protein
    See all BNP proteins and peptides

  • Purity

    > 90 % SDS-PAGE.
    ab87200 is purified using conventional chromatography techniques.

  • Expression system

    Escherichia coli

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      MGSSHHHHHH SSGLVPRGSH MHPLGSPGSA SDLETSGLQE QRNHLQGKLS ELQVEQTSLE PLQESPRPTG VWKSREVATE GIRGHRKMVL YTLRAPRSPK MVQGSGCFGR KMDRISSSSG LGCKVLRRH

Specifications

Our Abpromise guarantee covers the use of ab87200 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    pH: 7.40
    Constituents: PBS, 20% Glycerol

General Info

  • Alternative names

    • BNP(1-28)
    • BNP(1-29)
    • BNP(1-30)
    • BNP(1-32)
    • BNP(2-31)
    • BNP(3-29)
    • BNP(3-30)
    • BNP(3-32)
    • BNP(4-27)
    • BNP(4-29)
    • BNP(4-30)
    • BNP(4-31)
    • BNP(4-32)
    • BNP(5-29)
    • BNP(5-31)
    • BNP(5-32)
    • Brain natriuretic peptide 32
    • Brain type natriuretic peptide
    • Gamma brain natriuretic peptide
    • Natriuretic peptide B
    • Natriuretic peptide precursor B
    • natriuretic peptide, brain type
    • Natriuretic peptides B
    • natriuretic protein
    • NPPB
    see all

  • Relevance

    Brain natriuretic peptide (BNP) circulates in blood as a peptide hormone with natriuretic, vasodilatory and renin inhibitory properties. BNP is secreted predominantly by the left ventricular myocytes in response to volume expansion and pressure overload. BNP belongs to a family of structurally similar peptide hormones, which includes atrial natriuretic peptide (ANP), BNP, C type natriuretic peptide (CNP) and urodilatin. These peptides are characterized by a common 17 amino acid ring structure with a disulfide bond between two cystein residues. This ring structure shows high homology between different natriuretic peptides (eleven of the 17 amino acid residues are homologous in the ring of each of the natriuretic peptides). BNP is a 32 amino acid peptide with disulfide bond between the cysteine residues Cys10 and Cys26. In earlier studies it has been demonstrated that BNP concentration in blood increases with the severity of congestive heart failure. Quantitative measurement of BNP in blood provides an objective indicator of congestive heart failure severity.

  • Cellular localization

    Secreted

Images

  • SDS-PAGE - Recombinant Human BNP protein (ab87200)
    SDS-PAGE - Recombinant Human BNP protein (ab87200)
    15% SDS-PAGE showing ab87200 at approximately 14kDa (3µg).

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

References

Publishing research using ab87200? Please let us know so that we can cite the reference in this datasheet.

ab87200 has not yet been referenced specifically in any publications.

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