Description

  • Product name

    Recombinant Human Bone Sialoprotein (His tag)
    See all Bone Sialoprotein proteins and peptides
  • Purity

    > 90 % SDS-PAGE.
    ab219248 was purified using conventional chromatography techniques.
  • Endotoxin level

    < 1.000 Eu/µg
  • Expression system

    Baculovirus infected insect cells
  • Accession

  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Predicted molecular weight

      35 kDa including tags
    • Amino acids

      17 to 317
    • Tags

      His tag C-Terminus
    • Additional sequence information

      This product is for the mature full length protein. The signal peptide is not included. (NP_004958).

Specifications

Our Abpromise guarantee covers the use of ab219248 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 7.4
    Constituents: 0.002% PMSF, 10% Glycerol, 89% PBS

General Info

  • Alternative names

    • BNSP
    • Bone sialoprotein 2
    • Bone sialoprotein II
    • BSP
    • BSP II
    • BSPII
    • Cell binding sialoprotein
    • Cell-binding sialoprotein
    • IBSP
    • Integrin binding sialoprotein
    • Integrin-binding sialoprotein
    • SIAL_HUMAN
    • SPII
    see all
  • Function

    Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Promotes Arg-Gly-Asp-dependent cell attachment.
  • Post-translational
    modifications

    N-glycosylated; glycans consist of sialated and core-fucosylated bi-, tri- and tetraantennary chains.
    O-glycosylated at eight sites; mucin-type glycans contain Gal, GlcNAc, GalNAc and terminal NeuAc.
    Sulfated on either Tyr-313 or Tyr-314.
  • Cellular localization

    Secreted.
  • Information by UniProt

Images

  • 15% SDS-PAGE analysis of ab219248 (3μg).

References

ab219248 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab219248.
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