The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Protein concentration is above or equal to 0.05 mg/ml.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.31% Glutathione, 0.79% Tris HCl
Bruno like 5, RNA binding protein (Drosophila)
Bruno like protein 5
Bruno-like protein 5
CUG BP and ETR 3 like factor 5
CUG-BP- and ETR-3-like factor 5
CUGBP Elav-like family member 5
CUGBP, Elav-like family member 5
RNA binding protein BRUNOL5
RNA-binding protein BRUNOL-5
RNA-binding protein implicated in the regulation of pre-mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Binds to muscle-specific splicing enhancer (MSE) intronic sites flanking the alternative exon 5 of TNNT2 pre-mRNA.
Expressed in brain.
Belongs to the CELF/BRUNOL family. Contains 3 RRM (RNA recognition motif) domains.