Recombinant Human BTN1A1 protein (Fc Chimera) (ab219661)

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Description

  • Product name

    Recombinant Human BTN1A1 protein (Fc Chimera)
    See all BTN1A1 proteins and peptides

  • Purity

    > 95 % SDS-PAGE.

  • Endotoxin level

    < 1.000 Eu/µg

  • Expression system

    HEK 293 cells

  • Accession

    Q13410

  • Protein length

    Protein fragment

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      APFDVIGPPEPILAVVGEDAELPCRLSPNASAEHLELRWFRKKVSPAVLV HRDGREQEAEQMPEYRGRATLVQDGIAKGRVALRIRGVRVSDDGEYTCFF REDGSYEEALVHLKVAALGSDPHISMQVQENGEICLECTSVGWYPEPQVQ WRTSKGEKFPSTSESRNPDEEGLFTVAASVIIRDTSAKNVSCYIQNLLLG QEKKVEISIPASSLPR

    • Predicted molecular weight

      51 kDa including tags

    • Amino acids

      27 to 242

    • Additional sequence information

      Extracellular domain of BTN1A1 fused with a Human IgG1 Fc tag at the C-terminus.

Specifications

Our Abpromise guarantee covers the use of ab219661 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot. Store at -20°C long term. For long term storage it is recommended to add a carrier protein on reconstitution (0.1% HSA or BSA).

    pH: 7.50
    Constituents: 0.61% Tris, 0.75% Glycine, 5% Trehalose, 0.44% L-Arginine, 0.87% Sodium chloride

  • Reconstitution
    Reconstitute the lyophilized product in sterile deionized water to a final concentration of 1 mg/mL. Solubilize for 30 to 60 minutes at room temperature with occasional gentle mixing. Carrier protein (0.1% HSA or BSA) is strongly recommended for further dilution and long term storage.

General Info

  • Alternative names

    • BT
    • BT1A1_HUMAN
    • BTN
    • BTN1
    • Btn1a1
    • butyrophilin
    • Butyrophilin subfamily 1 member A1
    • butyrophilin, subfamily 1, member A1
    see all

  • Function

    May function in the secretion of milk-fat droplets. May act as a specific membrane-associated receptor for the association of cytoplasmic droplets with the apical plasma membrane (By similarity). Inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion.

  • Sequence similarities

    Belongs to the immunoglobulin superfamily. BTN/MOG family.
    Contains 1 B30.2/SPRY domain.
    Contains 2 Ig-like V-type (immunoglobulin-like) domains.

  • Post-translational
    modifications

    N-glycosylated.

  • Cellular localization

    Membrane. Secreted.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant Human BTN1A1 protein (Fc Chimera) (ab219661)
    SDS-PAGE - Recombinant Human BTN1A1 protein (Fc Chimera) (ab219661)

    SDS-PAGE using ab219661 under reducing (Lane 1) and non-reducing (Lane 2) conditions. As a result of glycosylation, the reducing protein migrates at 55-66 kDa and the non-reducing protein migrates at 116-130 kDa.

References

ab219661 has not yet been referenced specifically in any publications.

Publishing research using ab219661? Please let us know so that we can cite the reference in this datasheet.

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