Recombinant Human CAMLG protein (ab158023)
- Datasheet
- References
- Protocols
Overview
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Product nameRecombinant Human CAMLG protein
See all CAMLG proteins and peptides -
Protein lengthFull length protein
Description
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NatureRecombinant
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SourceWheat germ
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Amino Acid Sequence
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SpeciesHuman
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SequenceMESMAVATDGGERPGVPAGSGLSASQRRAELRRRKLLMNSEQRINRIMGF HRPGSGAEEESQTKSKQQDSDKLNSLSVPSVSKRVVLGDSVSTGTTDQQG GVAEVKGTQLGDKLDSFIKPPECSSDVNLELRQRNRGDLTADSVQRGSRH GLEQYLSRFEEAMKLRKQLISEKPSQEDGNTTEEFDSFRIFRLVGCALLA LGVRAFVCKYLSIFAPFLTLQLAYMGLYKYFPKSEKKIKTTVLTAALLLS GIPAEVINRSMDTYSKMGEVFTDLCVYFFTFIFCHELLDYWGSEVP
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Amino acids1 to 296
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Tagsproprietary tag N-Terminus
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Specifications
Our Abpromise guarantee covers the use of ab158023 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
Western blot
ELISA
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FormLiquid
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Additional notesProtein concentration is above or equal to 0.05 mg/ml.
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00
Constituents: 0.31% Glutathione, 0.79% Tris HCl
General Info
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Alternative names
- calcium modulating cyclophilin ligand
- calcium modulating ligand
- Calcium signal modulating cyclophilin ligand
see all -
RelevanceThe immunosuppressant drug cyclosporin A blocks a calcium dependent signal from the T cell receptor (TCR) that normally leads to T cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin. [Entrez Gene]
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Cellular localizationMembrane; Multi pass membrane protein.
Images
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SDS-PAGE - Recombinant Human CAMLG protein (ab158023)ab158023 on a 12.5% SDS-PAGE stained with Coomassie Blue.
Datasheets and documents
References
ab158023 has not yet been referenced specifically in any publications.
