Description

  • Product name

    Recombinant Human carabin protein
  • Expression system

    Wheat germ
  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      MAQALGEDLVQPPELQDDSSSLGSDSELSGPGPYRQADRYGFIGGSSAEP GPGHPPADLIRQREMKWVEMTSHWEKTMSRRYKKVKMQCRKGIPSALRAR CWPLLCGAHVCQKNSPGTYQELAEAPGDPQWMETIGRDLHRQFPLHEMFV SPQGHGQQGLLQVLKAYTLYRPEQGYCQAQGPVAAVLLMHLPPEEAFWCL VQICEVYLPGYYGPHMEAVRLDAEVFMALLRRLLPHVHKHLQQVGVGPLL YLPEWFLCLFARSLPFPTVLRVWDAFLSEGARVLFRVGLTLVRLALGTAE QRGACPGLLETLGALRAIPPAQLQEEAFMSQVHSVVLSERDLQREIKAQL AQLPDSAPGPPPRPQVRLAGAQAIFEAQQLAGVRRGAKPEVPRIVVQPPE EPRPPRRKPQTRGKTFHGLLTRARGPPIEGPPRPQRGSTSFLDTRF
    • Amino acids

      1 to 446
    • Tags

      GST tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab166361 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    ELISA

  • Form

    Liquid
  • Additional notes

    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names

    • 1810062O14Rik
    • AI428527
    • Carabin
    • FLJ00332
    • MGC46488
    • RGD1311490
    • TB10C_HUMAN
    • TBC1 domain family member 10C
    • TBC1D10C
    see all
  • Function

    Inhibits the Ras signaling pathway through its intrinsic Ras GTPase-activating protein (GAP) activity. Acts as a negative feedback inhibitor of the calcineurin signaling pathway that also mediates crosstalk between calcineurin and Ras.
  • Tissue specificity

    Most abundant in spleen and peripheral blood leukocytes.
  • Sequence similarities

    Contains 1 Rab-GAP TBC domain.
  • Information by UniProt

Images

  • ab166361 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab166361 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab166361.
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