Recombinant Human Carbonic Anhydrase IX protein (His tag) (ab186087)

Overview

Description

  • Nature
    Recombinant
  • Source
    Baculovirus infected Sf9 cells
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      GPDQSHWRYG GDPPWPRVSP ACAGRFQSPV DIRPQLAAFC PALRPLELLG FQLPPLPELR LRNNGHSVQL TLPPGLEMAL GPGREYRALQ LHLHWGAAGR PGSEHTVEGH RFPAEIHVVH LSTAFARVDE ALGRPGGLAV LAAFLEEGPE ENSAYEQLLSR LEEIAEEGSE TQVPGLDISA LLPSDFSRYF QYEGSLTTPP CAQGVIWTVF NQTVMLSAKQL HTLSDTLWGP GDSRLQLNFR ATQPLNGRVI EASFPAGVDS SPRAAEPVQ LNSCLAAGD
    • Molecular weight
      30 kDa including tags
    • Amino acids
      137 to 414
    • Additional sequence information
      NP_001207

Specifications

Our Abpromise guarantee covers the use of ab186087 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity
    >95% by SDS-PAGE .
    The purity of ab186087 is >95% by SDS-PAGE under reducing conditions.
  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on Dry Ice. Store at -80°C.

    pH: 7.50
    Preservative: 0.33% Sodium azide
    Constituent: 0.79% Tris HCl

General Info

  • Alternative names
    • CA-IX
    • CA9
    • CAH9_HUMAN
    • CAIX
    • Carbonate dehydratase IX
    • Carbonic anhydrase 9
    • Carbonic anhydrase IX
    • Carbonic dehydratase
    • G250
    • Membrane antigen MN
    • MN
    • P54/58N
    • pMW1
    • RCC associated protein G250
    • RCC-associated antigen G250
    • Renal cell carcinoma-associated antigen G250
    see all
  • Function
    Reversible hydration of carbon dioxide. Participates in pH regulation. May be involved in the control of cell proliferation and transformation. Appears to be a novel specific biomarker for a cervical neoplasia.
  • Tissue specificity
    Expressed primarily in carcinoma cells lines. Expression is restricted to very few normal tissues and the most abundant expression is found in the epithelial cells of gastric mucosa.
  • Sequence similarities
    Belongs to the alpha-carbonic anhydrase family.
    Contains 1 alpha-carbonic anhydrase domain.
  • Post-translational
    modifications
    Asn-346 bears high-mannose type glycan structures.
  • Cellular localization
    Nucleus. Nucleus, nucleolus. Cell membrane. Cell projection, microvillus membrane. Found on the surface microvilli and in the nucleus, particularly in nucleolus.
  • Information by UniProt

References

ab186087 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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