Recombinant Human Caspase-14 protein (ab173054)
- Datasheet
- References
- Protocols
Overview
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Product nameRecombinant Human Caspase-14 protein
See all Caspase-14 proteins and peptides -
Protein lengthFull length protein
Description
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NatureRecombinant
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SourceEscherichia coli
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Amino Acid Sequence
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Accession
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SpeciesHuman
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SequenceMSNPRSLEEEKYDMSGARLALILCVTKAREGSEEDLDALEHMFRQLRFES TMKRDPTAEQFQEELEKFQQAIDSREDPVSCAFVVLMAHGREGFLKGEDG EMVKLENLFEALNNKNCQALRAKPKVYIIQACRGEQRDPGETVGGDEIVM VIKDSPQTIPTYTDALHVYSTVEGYIAYRHDQKGSCFIQTLVDVFTKRKG HILELLTEVTRRMAEAELVQEGKARKTNPEIQSTLRKRLYLQLEHHHHHH
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Molecular weight29 kDa including tags
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Amino acids1 to 242
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TagsHis tag C-Terminus
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Associated products
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Related Products
- Anti-Caspase-14 antibody (ab115275)
- Anti-Caspase-14 antibody [70A1426] (ab11920)
- Anti-Caspase-14 antibody (ab139741)
- Anti-6X His tag® antibody [HIS.H8] (ab18184)
- Anti-Caspase-14 antibody (ab26991)
- Anti-Caspase-14 antibody (ab45415)
- Anti-6X His tag® antibody [4D11] (ab5000)
- Anti-6X His tag® antibody - ChIP Grade (ab9108)
Specifications
Our Abpromise guarantee covers the use of ab173054 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
HPLC
SDS-PAGE
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Endotoxin level< 1.000 Eu/µg
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Purity>95% by SDS-PAGE .
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FormLiquid
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped on Dry Ice. Store at -20°C long term. Avoid freeze / thaw cycle.
pH: 7.40
Constituent: 100% PBS
General Info
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Alternative names
- Apoptosis related cysteine protease
- CASP 14
- CASP-14
see all -
FunctionBelieved to be a non-apoptotic caspase which is involved in epidermal differentiation. Seems to play a role in keratinocyte differentiation and cornification. Probably regulates maturation of the epidermis by proteolytically processing filaggrin.
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Tissue specificityExpressed in keratinocytes of adult skin suprabasal layers (from spinous layers to the stratum granulosum and stratum corneum) (at protein level). Expressed in keratinocytes of hair shaft and sebaceous glands (at protein level). In psoriatic skin only expressed at very low levels.
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Sequence similaritiesBelongs to the peptidase C14A family.
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Cellular localizationCytoplasm. Nucleus.
- Information by UniProt
Datasheets and documents
References
ab173054 has not yet been referenced specifically in any publications.
