Recombinant Human Caspase-2 protein (ab158032)

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SDS-PAGE - Recombinant Human Caspase-2 protein (ab158032)

    Key features and details

    • Expression system: Wheat germ
    • Tags: GST tag N-Terminus
    • Suitable for: ELISA, WB

    Description

    • Product name

      Recombinant Human Caspase-2 protein
      See all Caspase-2 proteins and peptides

    • Expression system

      Wheat germ

    • Accession

      P42575

    • Protein length

      Protein fragment

    • Animal free

      No

    • Nature

      Recombinant

      • Species

        Human

      • Sequence

        TLSGLQHVLPPLSCDYDLSLPFPVCESCPLYKKLRLSTDTVEHSLDNKDG PLCLQVKPCTPEFYQTHFQLAYRLQSRPRGLALVLSNVHFTGEKELEFRS

      • Amino acids

        121 to 220

      • Tags

        GST tag N-Terminus

    Specifications

    Our Abpromise guarantee covers the use of ab158032 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      ELISA

      Western blot

    • Form

      Liquid

    • Additional notes

       

       

    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

      pH: 8.00
      Constituents: 0.31% Glutathione, 0.79% Tris HCl

    General Info

    • Alternative names

      • CASP 2
      • CASP-2
      • Casp2
      • CASP2_HUMAN
      • Caspase 2
      • Caspase 2 apoptosis related cysteine peptidase
      • Caspase-2 subunit p12
      • Caspase2
      • ICH 1
      • ICH 1 protease
      • ICH 1L
      • ICH1
      • ICH1 protease
      • ICH1L
      • NEDD-2
      • NEDD2
      • Neural precursor cell expressed developmentally down-regulated protein 2
      • PPP1R57
      • Protease ICH-1
      • Protein phosphatase 1 regulatory subunit 57
      see all

    • Function

      Involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival.

    • Tissue specificity

      Expressed at higher levels in the embryonic lung, liver and kidney than in the heart and brain. In adults, higher level expression is seen in the placenta, lung, kidney, and pancreas than in the heart, brain, liver and skeletal muscle.

    • Sequence similarities

      Belongs to the peptidase C14A family.
      Contains 1 CARD domain.

    • Post-translational
      modifications

      The mature protease can process its own propeptide, but not that of other caspases.
    • Information by UniProt

    Images

    • SDS-PAGE - Recombinant Human Caspase-2 protein (ab158032)
      SDS-PAGE - Recombinant Human Caspase-2 protein (ab158032)
      ab158032 on a 12.5% SDS-PAGE stained with Coomassie Blue.

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    References (0)

    Publishing research using ab158032? Please let us know so that we can cite the reference in this datasheet.

    ab158032 has not yet been referenced specifically in any publications.

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