Recombinant Human Caspase-2 protein (ab158032)

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Overview

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Accession
      P42575
    • Species
      Human
    • Sequence
      TLSGLQHVLPPLSCDYDLSLPFPVCESCPLYKKLRLSTDTVEHSLDNKDG PLCLQVKPCTPEFYQTHFQLAYRLQSRPRGLALVLSNVHFTGEKELEFRS
    • Amino acids
      121 to 220
    • Tags
      proprietary tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab158032 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    Western blot

  • Form
    Liquid
  • Additional notes

    Protein concentration is above or equal to 0.05 mg/ml.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • CASP 2
    • CASP-2
    • Casp2
    • CASP2_HUMAN
    • Caspase 2
    • Caspase 2 apoptosis related cysteine peptidase
    • Caspase-2 subunit p12
    • Caspase2
    • ICH 1
    • ICH 1 protease
    • ICH 1L
    • ICH1
    • ICH1 protease
    • ICH1L
    • NEDD-2
    • NEDD2
    • Neural precursor cell expressed developmentally down-regulated protein 2
    • PPP1R57
    • Protease ICH-1
    • Protein phosphatase 1 regulatory subunit 57
    see all
  • Function
    Involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival.
  • Tissue specificity
    Expressed at higher levels in the embryonic lung, liver and kidney than in the heart and brain. In adults, higher level expression is seen in the placenta, lung, kidney, and pancreas than in the heart, brain, liver and skeletal muscle.
  • Sequence similarities
    Belongs to the peptidase C14A family.
    Contains 1 CARD domain.
  • Post-translational
    modifications
    The mature protease can process its own propeptide, but not that of other caspases.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant Human Caspase-2 protein (ab158032)
    SDS-PAGE - Recombinant Human Caspase-2 protein (ab158032)
    ab158032 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab158032 has not yet been referenced specifically in any publications.

Publishing research using ab158032? Please let us know so that we can cite the reference in this datasheet.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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