Recombinant Human Cathepsin B protein (ab151914)

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Overview

Description

  • Nature

    Recombinant

  • Source

    HEK 293 cells
  • Amino Acid Sequence
    • Accession
      P07858

    • Species

      Human

    • Sequence

      RSRPSFHPVSDELVNYVNKRNTTWQAGHNFYNVDMGYLKRLCGTFLGGPK PPQRVMFTED LKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNA HVSVEVSAED LLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPC EHHVNGSRPP CTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNG PVEGAFSVYS DFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDN GFFKILRGQD HCGIESEVVAGIPRTDQYWEKIVDHHHHHH

    • Molecular weight

      37 kDa including tags

    • Amino acids

      18 to 339

    • Tags

      His tag C-Terminus

Specifications

Our Abpromise guarantee covers the use of ab151914 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    HPLC

  • Endotoxin level

    < 1.000 Eu/µg

  • Purity

    > 95 % SDS-PAGE.
    Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE

  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 0.88% Sodium chloride

    0.2 µm filtered solution

General Info

  • Alternative names

    • Amyloid precursor protein secretase
    • APP secretase
    • APPS
    • CATB_HUMAN
    • Cathepsin B heavy chain
    • Cathepsin B1
    • CathepsinB
    • CPSB
    • CTSB
    • cysteine protease
    • OTTHUMP00000116009
    • OTTHUMP00000229510
    • OTTHUMP00000229511
    • OTTHUMP00000229512
    • OTTHUMP00000229514
    • OTTHUMP00000229515
    • OTTHUMP00000229516
    • Preprocathepsin B
    see all

  • Function

    Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis.

  • Sequence similarities

    Belongs to the peptidase C1 family.

  • Cellular localization

    Lysosome. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
  • Information by UniProt

References

ab151914 has not yet been referenced specifically in any publications.

Publishing research using ab151914? Please let us know so that we can cite the reference in this datasheet.

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