Recombinant human Cathepsin L protein (Active) (ab174030)

Overview

Description

  • Nature
    Recombinant
  • Source
    HEK 293 cells
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      TLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYR EGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRS VDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLV DCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKY SVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEP DCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKD RRNHCGIASAASYPTV
    • Molecular weight
      37 kDa including tags
    • Amino acids
      18 to 333
    • Tags
      His tag C-Terminus

Specifications

Our Abpromise guarantee covers the use of ab174030 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity

    Measured by its binding ability in a functional ELISA.

    Immobilized Human CD74 at 5 μg/ml ( 100 μl/well ) can bind biotinylated Human Cathepsin L with a linear range of 25 - 400 ng/ml.

  • Applications

    ELISA

    Functional Studies

    SDS-PAGE

  • Endotoxin level
    < 1.000 Eu/µg
  • Purity
    > 98 % SDS-PAGE.

  • Form
    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at 4°C prior to reconstitution. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • cathepsin L, 1 b
    • Cathepsin L1
    • Cathepsin L1 light chain
    • CathepsinL
    • CATL
    • CATL1_HUMAN
    • cb15
    • CTSL
    • CTSL1
    • ctsl1b
    • FLJ31037
    • hgg1
    • Major excreted protein
    • MEP
    • MGC123162
    • wu:fb30g09
    see all
  • Function
    Important for the overall degradation of proteins in lysosomes.
  • Sequence similarities
    Belongs to the peptidase C1 family.
  • Cellular localization
    Lysosome.
  • Information by UniProt

Images

  • SDS-PAGE analysis of reduced ab174030 and staining overnight with Coomassie Blue. DTT-reduced Protein migrates as 10 kDa and 34 kDa due to glycosylation,corresponding to the propeptide and the mature form respectively.

References

ab174030 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab174030.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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