Recombinant Human CBX1 / HP1 beta protein (ab109847)
Key features and details
- Expression system: Escherichia coli
- Purity: > 85% SDS-PAGE
- Tags: His tag N-Terminus
- Suitable for: SDS-PAGE, WB
Description
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Product name
Recombinant Human CBX1 / HP1 beta protein
See all CBX1 / HP1 beta proteins and peptides -
Purity
> 85 % SDS-PAGE.
ab109847 is purified using conventional chromatography techniques. -
Expression system
Escherichia coli -
Accession
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Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Sequence
MGSSHHHHHHSSGLVPRGSHMGKKQNKKKVEEVLEEEEEEYVVEKVLDRR VVKGKVEYLLKWKGFSDEDNTWEPEENLDCPDLIAEFLQSQKTAHETDKS EGGKRKADSDSEDKGEESKPKKKKEESEKPRGFARGLEPERIIGATDSSG ELMFLMKWKNSDEADLVPAKEANVKCPQVVISFYEERLTWHSYPSEDDDK KDDKN -
Predicted molecular weight
24 kDa including tags -
Amino acids
1 to 185 -
Tags
His tag N-Terminus
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Associated products
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Related Products
Specifications
Our Abpromise guarantee covers the use of ab109847 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
SDS-PAGE
Western blot
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Mass spectrometry
MALDI-TOF -
Form
Liquid -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 8.00
Constituents: 0.0308% DTT, 0.316% Tris HCl, 20% Glycerol (glycerin, glycerine), 0.058% Sodium chloride
General Info
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Alternative names
- CBX
- CBX 1
- Cbx1
see all -
Function
Component of heterochromatin. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane. -
Tissue specificity
Expressed in all adult and embryonic tissues. -
Sequence similarities
Contains 2 chromo domains. -
Post-translational
modificationsNot phosphorylated.
Ubiquitinated. -
Cellular localization
Nucleus. Unassociated with chromosomes during mitosis. - Information by UniProt
Images
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SDS-PAGE - Recombinant Human CBX1 / HP1 beta protein (ab109847)15% SDS-PAGE showing ab109847 at approximately 23.6 kDa (3µg).
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Western blot - Recombinant Human CBX1 / HP1 beta protein (ab109847)
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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Datasheet download
References (0)
ab109847 has not yet been referenced specifically in any publications.
