Description

  • Product name

    Recombinant Human CCDC6 protein
  • Expression system

    Wheat germ
  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      MADSASESDTDGAGGNSSSSAAMQSSCSSTSGGGGGGGGGGGGGKSGGIV ISPFRLEELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVT IQARAEQEEEFISNTLFKKIQALQKEKETLAVNYEKEEEFLTNELSRKLM QLQHEKAELEQHLEQEQEFQVNKLMKKIKKLENDTISKQLTLEQLRREKI DLENTLEQEQEALVNRLWKRMDKLEAEKRILQEKLDQPVSAPPSPRDISM EIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEKMAQYLEEERHMREE NLRLQRKLQREMERREALCRQLSESESSLEMDDERYFNEMSAQGLRPRTV SSPIPYTPSPSSSRPISPGLSYASHTVGFTPPTSLTRAGMSYYNSPGLHV QHMGTSHGITRPSPRRSNSPDKFKRPTPPPSPNTQTPVQPPPPPPPPPMQ PTVPSAATSQPTPSQHSAHTSSQP
    • Amino acids

      1 to 474
    • Tags

      GST tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab159931 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    Western blot

  • Form

    Liquid
  • Additional notes

    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names

    • CCDC 6
    • CCDC6
    • CCDC6_HUMAN
    • Coiled coil domain containing 6
    • Coiled coil domain containing protein 6
    • Coiled-coil domain-containing protein 6
    • D10S170
    • FLJ32286
    • H4
    • Papillary thyroid carcinoma encoded protein
    • Papillary thyroid carcinoma-encoded protein
    • Protein H4
    • PTC
    • TPC
    • TST 1
    • TST1
    see all
  • Tissue specificity

    Ubiquitously expressed.
  • Involvement in disease

    Defects in CCDC6 are a cause of thyroid papillary carcinoma (TPC) [MIM:188550]. TPC is a common tumor of the thyroid that typically arises as an irregular, solid or cystic mass from otherwise normal thyroid tissue. Papillary carcinomas are malignant neoplasm characterized by the formation of numerous, irregular, finger-like projections of fibrous stroma that is covered with a surface layer of neoplastic epithelial cells. Note=A chromosomal aberration involving CCDC6 is found in thyroid papillary carcinomas. Inversion inv(10)(q11.2;q21) generates the RET/CCDC6 (PTC1) oncogene.
  • Domain

    The protein has mostly an alpha helical conformation similar to myosin heavy-chain tail that might adopt a coiled-coil conformation.
  • Cellular localization

    Cytoplasm. Cytoplasm > cytoskeleton. May be a cytoskeletal protein.
  • Information by UniProt

Images

  • ab159931 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab159931 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab159931.
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