Recombinant Human CD10 protein (ab155720)

Submit a review Submit a question

Description

  • Product name

    Recombinant Human CD10 protein
    See all CD10 proteins and peptides

  • Purity

    > 95 % SDS-PAGE.

  • Endotoxin level

    < 1.000 Eu/µg

  • Expression system

    HEK 293 cells

  • Accession

    P08473

  • Protein length

    Protein fragment

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      YDDGICKSSDCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETS SRYGNFDILRDELEVVLKDVLQEPKTEDIVAVQKAKALYRSCINESAIDS RGGEPLLKLLPDIYGWPVATENWEQKYGASWTAEKAIAQLNSKYGKKVLI NLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEACTAYVDFMIS VARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLYN KMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEY LTKLKPILTKYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGT TSETATWRRCANYVNGNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVF IQTLDDLTWMDAETKKRAEEKALAIKERIGYPDDIVSNDNKLNNEYLELN YKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFYSSGRN QIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDG DLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIAD NGGLGQAYRAYQNYIKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPE YAVNSIKTDVHSPGNFRIIGTLQNSAEFSEAFHCRKNSYMNPEKKCRVW

    • Predicted molecular weight

      107 kDa including tags

    • Amino acids

      52 to 750

    • Tags

      Fc tag N-Terminus

    • Additional sequence information

      This protein carries a human IgG1 Fc tag at the N-terminus.

Associated products

    Specifications

    Our Abpromise guarantee covers the use of ab155720 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

    • Form

      Lyophilized
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

      pH: 7.50
      Constituents: Tris, Glycine, L-Arginine, Sodium chloride

    • Reconstitution
      Reconstitute with sterile deionized water to a concentration of 400 µg/ml.

    General Info

    • Alternative names

      • Atriopeptidase
      • CALLA
      • CD10
      • CD10 antigen
      • Common acute lymphocytic leukemia antigen
      • DKFZp686O16152
      • EC 3.4.24.11
      • Enkephalinase
      • EPN
      • Membrane metallo endopeptidase
      • Membrane metallo endopeptidase (neutral endopeptidase, enkephalinase)
      • Membrane metallo endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10)
      • Membrane metallo endopeptidase variant 1
      • Membrane metallo endopeptidase variant 2
      • Membrane metalloendopeptidase
      • Membrane metalloendopeptidase neutral endopeptidase enkephalinase
      • Membrane metalloendopeptidase neutral endopeptidase enkephalinase CALLA CD10
      • Membrane metalloendopeptidase variant 1
      • Membrane metalloendopeptidase variant 2
      • MGC126681
      • MGC126707
      • MME
      • NEP
      • NEP_HUMAN
      • Neprilysin
      • neprilysin-390
      • neprilysin-411
      • Neutral endopeptidase
      • Neutral endopeptidase 24.11
      • Neutral endopeptidase, membrane-associated
      • SFE
      • Skin fibroblast elastase
      see all

    • Function

      Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers.

    • Sequence similarities

      Belongs to the peptidase M13 family.

    • Cellular localization

      Cell membrane.
    • Information by UniProt

    Images

    • SDS-PAGE - Recombinant Human CD10 protein (ab155720)
      SDS-PAGE - Recombinant Human CD10 protein (ab155720)

      ab155720 on SDS-PAGE under reducing conditions. The gel was stained overnight with Coomassie Blue. The protein migrates as 106-120 kDa under reducing conditions due to glycosylation.

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    References (0)

    Publishing research using ab155720? Please let us know so that we can cite the reference in this datasheet.

    ab155720 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    Show All Reviews Q&A
    Submit a review Submit a question

    There are currently no Customer reviews or Questions for ab155720.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com