Recombinant Human CD11c protein (ab158776)
- Datasheet
- References
- Protocols
Overview
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Product nameRecombinant Human CD11c protein
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Protein lengthProtein fragment
Description
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NatureRecombinant
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SourceWheat germ
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Amino Acid Sequence
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SpeciesHuman
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SequenceHECGRNMYLTGLCFLLGPTQLTQRLPVSRQECPRQEQDIVFLIDGSGSIS SRNFATMMNFVRAVISQFQRPSTQFSLMQFSNKFQTHFTFEEFRRSSNPL SLLASVHQLQ
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Amino acids114 to 223
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TagsGST tag N-Terminus
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Specifications
Our Abpromise guarantee covers the use of ab158776 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
Western blot
ELISA
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FormLiquid
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Additional notesProtein concentration is above or equal to 0.05 mg/ml.
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00
Constituents: 0.31% Glutathione, 0.79% Tris HCl
General Info
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Alternative names
- 95
- 95 alpha chain
- CD 11c
see all -
FunctionIntegrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis.
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Tissue specificityPredominantly expressed in monocytes and granulocytes.
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Sequence similaritiesBelongs to the integrin alpha chain family.
Contains 7 FG-GAP repeats.
Contains 1 VWFA domain. -
DomainThe integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.
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Cellular localizationMembrane.
- Information by UniProt
Images
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SDS-PAGE - Recombinant Human CD11c protein (ab158776)ab158776 on a 12.5% SDS-PAGE stained with Coomassie Blue. Predicted MW (kDa): 37.84.
Datasheets and documents
References
ab158776 has not yet been referenced specifically in any publications.
