Recombinant Human CD11c protein (ab158776)

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SDS-PAGE - Recombinant Human CD11c protein (ab158776)

    Key features and details

    • Expression system: Wheat germ
    • Tags: GST tag N-Terminus
    • Suitable for: WB, ELISA

    Description

    • Product name

      Recombinant Human CD11c protein

    • Expression system

      Wheat germ

    • Protein length

      Protein fragment

    • Animal free

      No

    • Nature

      Recombinant

      • Species

        Human

      • Sequence

        HECGRNMYLTGLCFLLGPTQLTQRLPVSRQECPRQEQDIVFLIDGSGSIS SRNFATMMNFVRAVISQFQRPSTQFSLMQFSNKFQTHFTFEEFRRSSNPL SLLASVHQLQ

      • Amino acids

        114 to 223

      • Tags

        GST tag N-Terminus

    Specifications

    Our Abpromise guarantee covers the use of ab158776 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      Western blot

      ELISA

    • Form

      Liquid

    • Additional notes

       

       

    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

      pH: 8.00
      Constituents: 0.31% Glutathione, 0.79% Tris HCl

    General Info

    • Alternative names

      • 95
      • 95 alpha chain
      • CD 11c
      • CD11 antigen like family member C
      • CD11 antigen-like family member C
      • CD11c
      • CD11c antigen
      • Complement component 3 receptor 4 subunit
      • CR4
      • Integrin alpha X
      • Integrin alpha X chain
      • Integrin alpha-X
      • Integrin aX
      • Integrin subunit alpha X
      • integrin, alpha X (antigen CD11C (p150), alpha polypeptide)
      • integrin, alpha X (complement component 3 receptor 4 subunit
      • ITAX_HUMAN
      • ITGAX
      • Leu M5
      • LEU M5 alpha subunit
      • Leukocyte adhesion glycoprotein p150
      • Leukocyte adhesion glycoprotein p150 95 alpha chain
      • Leukocyte adhesion receptor p150
      • Leukocyte adhesion receptor p150 95
      • Leukocyte surface antigen p150 95 alpha subunit
      • Leukocyte surface antigen p150 alpha subunit
      • Myeloid membrane antigen alpha subunit
      • p150
      • p150 95 integrin alpha chain
      • p150/95
      • SLEB6
      see all

    • Function

      Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis.

    • Tissue specificity

      Predominantly expressed in monocytes and granulocytes.

    • Sequence similarities

      Belongs to the integrin alpha chain family.
      Contains 7 FG-GAP repeats.
      Contains 1 VWFA domain.

    • Domain

      The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.

    • Cellular localization

      Membrane.
    • Information by UniProt

    Images

    • SDS-PAGE - Recombinant Human CD11c protein (ab158776)
      SDS-PAGE - Recombinant Human CD11c protein (ab158776)

      ab158776 on a 12.5% SDS-PAGE stained with Coomassie Blue. Predicted MW (kDa): 37.84.

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    References (0)

    Publishing research using ab158776? Please let us know so that we can cite the reference in this datasheet.

    ab158776 has not yet been referenced specifically in any publications.

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