Overview

  • Product name

    Recombinant Human CD1E protein (denatured)
  • Protein length

    Protein fragment
  • Description

    Recombinant Human CD1E protein

Description

  • Nature

    Recombinant
  • Source

    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species

      Human
    • Sequence

      MGSSHHHHHH SSGLVPRGSH MGSEEQLSFR MLQTSSFANH SWAHSEGSGW LGDLQTHGWD TVLGTIRFLK PWSHGNFSKQ ELKNLQSLFQ LYFHSFIQIV QASAGQFQLE YPFEIQILAG CRMNAPQIFL NMAYQGSDFL SFQGISWEPS PGAGIRAQNI CKVLNRYLDI KEILQSLLGH TCPRFLAGLM EAGESELKRK VKPEAWLSCG PSPGPGRLQL VCHVSGFYPK PVWVMWMRGE QEQRGTQRGD VLPNADETWY LRATLDVAAG EAAGLSCRVK HSSLGGHDLI IHWGGYS
    • Molecular weight

      33 kDa including tags
    • Amino acids

      30 to 305
    • Tags

      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab177643 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity

    > 85 % SDS-PAGE.

  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

General Info

  • Alternative names

    • CD_antigen=CD1e
    • CD1A
    • CD1e
    • CD1e antigen
    • CD1E antigen, e polypeptide
    • CD1e molecule
    • CD1E_HUMAN
    • Differentiation antigen CD1-alpha-3
    • hCD1e
    • Leukocyte differentiation antigen
    • R2
    • R2G1
    • sCD1e
    • soluble
    • T-cell surface glycoprotein CD1e
    • T-cell surface glycoprotein CD1e, membrane-associated
    • T-cell surface glycoprotein CD1e, soluble
    see all
  • Function

    T-cell surface glycoprotein CD1e, soluble binds diacetylated lipids, including phosphatidyl inositides and diacylated sulfoglycolipids, and is required for the presentation of glycolipid antigens on the cell surface. The membrane-associated form is not active.
  • Tissue specificity

    Expressed on cortical thymocytes, dendritic cells, Langerhans cells, on certain T-cell leukemias, and in various other tissues.
  • Sequence similarities

    Contains 1 Ig-like (immunoglobulin-like) domain.
  • Post-translational
    modifications

    Mono-ubiquitinated.
    Proteolytically cleaved in late endosomes to yield a soluble form.
  • Cellular localization

    Lysosome lumen and Golgi apparatus membrane. Early endosome. Late endosome. Predominantly localized in the trans-Golgi network in immature dendritic cells, and as a cleaved, soluble protein in the lysosome lumen of mature dendritic cells.
  • Information by UniProt

Images

  • 15% SDS-PAGE analysis of ab177643 (3ug)

References

ab177643 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab177643.
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