Recombinant Human CD2 protein (ab174026)

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Description

  • Product name

    Recombinant Human CD2 protein
    See all CD2 proteins and peptides

  • Purity

    > 98 % SDS-PAGE.

  • Endotoxin level

    < 1.000 Eu/µg

  • Expression system

    HEK 293 cells

  • Accession

    P06729

  • Protein length

    Protein fragment

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      KEITNALETWGALGQDINLDIPSFQMSDDIDDIKWEKTSDKKKIAQFRKE KETFKEKDTYKLFKNGTLKIKHLKTDDQDIYKVSIYDTKGKNVLEKIFDL KIQERVSKPKISWTCINTTLTCEVMNGTDPELNLYQDGKHLKLSQRVITH KWTTSLSAKFKCTAGNKVSKESSVEPVSCPEKGLD

    • Predicted molecular weight

      23 kDa including tags

    • Amino acids

      25 to 209

    • Tags

      His tag C-Terminus

    • Additional sequence information

      Extracellular domain.

Specifications

Our Abpromise guarantee covers the use of ab174026 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at 4°C prior to reconstitution. Store at -20°C or -80°C.

    pH: 7.40
    Constituents: 95% PBS, 5% Trehalose

  • Reconstitution
    It is recommended to reconstitute in 50 µl sterile deionized water to a final concentration of 1 mg/ml. Solubilize for 30 to 60 minutes at room temperature with occasional gentle mixing. Carrier protein (0.1% HSA or BSA) is strongly recommended for further dilution and long term storage. After reconstitution store under sterile conditions for 1 month at 4°C - 8°C or 3 months at -20°C to -80°C.

General Info

  • Alternative names

    • CD 2
    • CD2
    • CD2 antigen
    • CD2 antigen (p50), sheep red blood cell receptor
    • CD2 molecule
    • CD2_HUMAN
    • Erythrocyte receptor
    • FLJ46032
    • LFA-2
    • LFA-3 receptor
    • LFA2
    • LFA3 receptor
    • Ly-37
    • Lymphocyte function antigen 2
    • lymphocyte-function antigen-2
    • OTTHUMP00000024366
    • Rosette receptor
    • Sheep erythrocyte receptor
    • SRBC
    • T cell surface antigen CD2
    • T-cell surface antigen CD2
    • T-cell surface antigen T11/Leu-5
    • T-lymphocyte surface CD2 antigen
    • T11
    see all

  • Function

    CD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function.

  • Sequence similarities

    Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
    Contains 1 Ig-like V-type (immunoglobulin-like) domain.

  • Cellular localization

    Membrane.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant Human CD2 protein (ab174026)
    SDS-PAGE - Recombinant Human CD2 protein (ab174026)

    SDS-PAGE analysis of reduced ab174026 stained overnight with Coomassie Blue.

    DTT-reduced Protein migrates at 33-40 kDa due to glycosylation.

References

ab174026 has not yet been referenced specifically in any publications.

Publishing research using ab174026? Please let us know so that we can cite the reference in this datasheet.

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