Recombinant Human CD32A protein (ab151359)

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Key features and details

  • Expression system: HEK 293 cells
  • Purity: > 95% SDS-PAGE
  • Endotoxin level: < 1.000 Eu/µg
  • Tags: His tag C-Terminus
  • Suitable for: SDS-PAGE, HPLC

Description

  • Product name

    Recombinant Human CD32A protein
    See all CD32A proteins and peptides

  • Purity

    > 95 % SDS-PAGE.
    Purity is greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.

  • Endotoxin level

    < 1.000 Eu/µg

  • Expression system

    HEK 293 cells

  • Accession

    P12318

  • Protein length

    Protein fragment

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      QAAPPKAVLKLEPPWINVLQEDSVTLTCQGARSPESDSIQWFHNGNLIPT HTQPSYRFKANNNDSGEYTCQTGQTSLSDPVHLTVLSEWLVLQTPHLEFQ EGETIMLRCHSWKDKPLVKVTFFQNGKSQKFSRLDPTFSIPQANHSHSGD YHCTGNIGYTLFSSKPVTITVQVPSMGSSSPMGIIVDHHHHHH

    • Predicted molecular weight

      22 kDa including tags

    • Amino acids

      34 to 219

    • Tags

      His tag C-Terminus

Specifications

Our Abpromise guarantee covers the use of ab151359 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    HPLC

  • Form

    Lyophilized
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -80°C.

    pH: 7.40
    Constituents: 0.88% Sodium chloride, 99% Phosphate Buffer

  • Reconstitution
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in 1X PBS. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

General Info

  • Alternative names

    • CD32
    • CD32 antigen
    • CDw32
    • Fc fragment of IgG, low affinity IIa, receptor (CD32)
    • Fc fragment of IgG, low affinity IIa, receptor for (CD32)
    • Fc gamma RII a
    • Fc gamma RIIa
    • Fc-gamma RII-a
    • Fc-gamma-RIIa
    • FCG2
    • FCG2A_HUMAN
    • FcGR
    • FCGR2
    • FCGR2A
    • FCGR2A1
    • FcRII a
    • FcRII-a
    • IGFR2
    • IgG Fc receptor II a
    • IgG Fc receptor II-a
    • Immunoglobulin G Fc receptor II
    • low affinity immunoglobulin gamma Fc region receptor II a
    • Low affinity immunoglobulin gamma Fc region receptor II-a
    see all

  • Function

    Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens.

  • Tissue specificity

    Found on monocytes, neutrophils and eosinophil platelets.

  • Sequence similarities

    Contains 2 Ig-like C2-type (immunoglobulin-like) domains.

  • Post-translational
    modifications

    Phosphorylated by SRC-type Tyr-kinases such as LYN, BLK, FYN, HCK and SYK.

  • Cellular localization

    Cell membrane.
  • Information by UniProt

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

References (0)

Publishing research using ab151359? Please let us know so that we can cite the reference in this datasheet.

ab151359 has not yet been referenced specifically in any publications.

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