Recombinant Human CD43 protein (ab171717)

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Description

  • Product name

    Recombinant Human CD43 protein

  • Purity

    > 85 % SDS-PAGE.
    ab171717 was purified by anion-exchange and gel-filtration chromatography techniques.

  • Expression system

    Escherichia coli

  • Accession

    P16150

  • Protein length

    Protein fragment

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      MGSSHHHHHH SSGLVPRGSH MGSSTTAVQT PTSGEPLVST SEPLSSKMYT TSITSDPKAD STGDQTSALP PSTSINEGSP LWTSIGASTG SPLPEPTTYQ EVSIKMSSVP QETPHATSHP AVPITANSLG SHTVTGGTIT TNSPETSSRT SGAPVTTAAS SLETSRGTSG PPLTMATVSL ETSKGTSGPP VTMATDSLET STGTTGPPVT MTTGSLEPSS GASGPQVSSV KLSTMMSPTT STNASTVPFR NPDENSR

    • Predicted molecular weight

      26 kDa including tags

    • Amino acids

      20 to 253

    • Tags

      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab171717 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Mass Spectrometry

  • Mass spectrometry

    MALDI-TOF

  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 10% Glycerol, 0.88% Sodium chloride

General Info

  • Alternative names

    • CD 43
    • CD43
    • CD43 antigen
    • Galactoglycoprotein
    • GALGP
    • GPL 115
    • GPL115
    • Human gene for sialophorin
    • Leucocyte sialoglycoprotein
    • LEUK_HUMAN
    • Leukocyte large sialoglycoprotein
    • Leukocyte sialoglycoprotein
    • Leukosialin
    • LSN
    • Ly-48
    • Sialophorin
    • sialophorin (gpL115, leukosialin, CD43)
    • Spn
    see all

  • Function

    One of the major glycoproteins of thymocytes and T lymphocytes. Plays a role in the physicochemical properties of the T-cell surface and in lectin binding. Presents carbohydrate ligands to selectins. Has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. Is a counter receptor for SN/Siglec-1 (By similarity). During T-cell activation is actively removed from the T-cell-APC (antigen-presenting cell) contact site thus suggesting a negative regulatory role in adaptive immune response.

  • Tissue specificity

    Cell surface of thymocytes, T-lymphocytes, neutrophils, plasma cells and myelomas.

  • Post-translational
    modifications

    Glycosylated; has a high content of sialic acid and O-linked carbohydrate structures.

  • Cellular localization

    Membrane.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant Human CD43 protein (ab171717)
    SDS-PAGE - Recombinant Human CD43 protein (ab171717)
    15% SDS-PAGE analysis of ab171717 (3µg).

References

ab171717 has not yet been referenced specifically in any publications.

Publishing research using ab171717? Please let us know so that we can cite the reference in this datasheet.

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