Overview

  • Product name

    Recombinant Human CD72 protein (Fc Chimera)
  • Protein length

    Protein fragment

Description

  • Nature

    Recombinant
  • Source

    HEK 293 cells
  • Amino Acid Sequence
    • Accession
    • Species

      Human
    • Sequence

      ETLQ SEEQQRRALE QKLSNMENRL KPFFTCGSAD TCCPSGWIMH QKSCFYISLT SKNWQESQKQ CETLSSKLAT FSEIYPQSHS YYFLNSLLPN GGSGNSYWTG LSSNKDWKLT DDTQRTRTYA QSSKCNKVHK TWSWWTLESE SCRSSLPYIC EMTAFRFPD
    • Molecular weight

      54 kDa including tags
    • Amino acids

      117 to 359
    • Additional sequence information

      Fused with the Fc region of Human IgG1 at the C-terminus.

Specifications

Our Abpromise guarantee covers the use of ab191648 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Endotoxin level

    < 1.000 Eu/µg
  • Purity

    > 95 % SDS-PAGE.

  • Form

    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at 4°C prior to reconstitution. Store at -80°C. Avoid freeze / thaw cycle.

    pH: 7.50
    Constituents: 0.61% Tris, 0.75% Glycine

    5-10% trehalose is commonly used for freeze drying, and after reconstitution, the trehalose is mostly about 3-5%.
    Lyophilized from 0.22 µm filtered solution

  • Reconstitution
    Reconstitute in 100 µl sterile deionized water to a final concentration of 1 mg/ml. Solubilize for 30 to 60 minutes at room temperature with occasional gentle mixing. Carrier protein (0.1% HSA or BSA) is strongly recommended for further dilution and long term storage.

General Info

  • Alternative names

    • B cell differentiation antigen CD72
    • B-cell differentiation antigen CD72
    • CD_antigen=CD72
    • CD72
    • CD72 antigen
    • CD72 molecule
    • CD72_HUMAN
    • CD72b
    • CD72c
    • Ly-19
    • Ly-32
    • Ly-m19
    • Lyb-2
    • Lyb2
    • LYB2, mouse, homolog of
    • Lymphocyte antigen 32
    • MGC108873
    see all
  • Function

    Plays a role in B-cell proliferation and differentiation.
  • Tissue specificity

    Pre-B-cells and B-cells but not terminally differentiated plasma cells.
  • Sequence similarities

    Contains 1 C-type lectin domain.
  • Post-translational
    modifications

    Phosphorylated upon engagement of the B-cell receptor, probably by LYN or SYK. Phosphorylation at Tyr-7 is important for interaction with PTPN6/SHP-1.
  • Cellular localization

    Membrane.
  • Information by UniProt

Images

  • SDS-PAGE analysis of DTT reduced ab191648 with staining overnight with Coomassie blue. DTT-reduced protein migrates as 60-65 kDa due to glycosylation.

References

ab191648 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab191648.
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