Recombinant Human CD8 alpha protein (ab267853)
Key features and details
- Expression system: Mammalian
- Purity: > 90% SDS-PAGE
- Tags: His tag N-Terminus
- Suitable for: SDS-PAGE
Description
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Product name
Recombinant Human CD8 alpha protein
See all CD8 alpha proteins and peptides -
Purity
> 90 % SDS-PAGE.
NULL -
Expression system
Mammalian -
Accession
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Protein length
Protein fragment -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Sequence
SQFRVSPLDRTWNLGETVELKCQVLLSNPTSGCSWLFQPRGAAASPTFLL YLSQNKPKAAEGLDTQRFSGKRLGDTFVLTLSDFRRENEGYYFCSALSNS IMYFSHFVPVFLPAKPTTTPAPRPPTPAPTIASQPLSLRPEACRPAAGGA VHTRGLDFACD -
Predicted molecular weight
26 kDa -
Amino acids
22 to 182 -
Tags
His tag N-Terminus -
Additional sequence information
Extracellular Domain
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Associated products
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Related Products
Specifications
Our Abpromise guarantee covers the use of ab267853 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
SDS-PAGE
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Form
Liquid -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 7.2
Constituents: PBS, 6% Trehalose
General Info
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Alternative names
- alpha polypeptide (p32)
- CD_antigen=CD8a
- CD8
see all -
Function
Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. CD8 alpha chains binds to class I MHC molecules alpha-3 domains. -
Involvement in disease
Defects in CD8A are a cause of familial CD8 deficiency (CD8 deficiency) [MIM:608957]. Familial CD8 deficiency is a novel autosomal recessive immunologic defect characterized by absence of CD8+ cells, leading to recurrent bacterial infections. -
Sequence similarities
Contains 1 Ig-like V-type (immunoglobulin-like) domain. -
Post-translational
modificationsAll of the five most carboxyl-terminal cysteines form inter-chain disulfide bonds in dimers and higher multimers, while the four N-terminal cysteines do not. -
Cellular localization
Secreted and Cell membrane. - Information by UniProt
Images
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SDS-PAGE analysis of recombinant cd8 alpha protein (ab267853).
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Based on the SEQUEST from database of Mammalian Cell host and target protein, the LC-MS/MS Analysis result of ab267853 could indicate that this peptide is derived from Mammalian Cell-expressed Homo sapiens (Human) CD8alpha.
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Based on the SEQUEST from database of Mammalian Cell host and target protein, the LC-MS/MS Analysis result of ab267853 could indicate that this peptide is derived from Mammalian Cell-expressed Homo sapiens (Human) CD8alpha.
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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Datasheet download
References (0)
ab267853 has not yet been referenced specifically in any publications.