The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Protein concentration is above or equal to 0.05 mg/ml.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.31% Glutathione, 0.79% Tris HCl
Cell division cycle 25 homolog C
Cell division cycle 25C
Cell division cycle 25C protein
Dual specificity phosphatase Cdc25C
M phase inducer phosphatase 3
M-phase inducer phosphatase 3
Mitosis inducer CDC25
protein phosphatase 1, regulatory subunit 60
Functions as a dosage-dependent inducer in mitotic control. It is a tyrosine protein phosphatase required for progression of the cell cycle. It directly dephosphorylates CDK1 and activate its kinase activity.
Belongs to the MPI phosphatase family. Contains 1 rhodanese domain.
Expressed predominantly in G2 phase.
Phosphorylated by CHK1 on Ser-216. This phosphorylation creates a binding site for 14-3-3 protein and inhibits the phosphatase. Phosphorylated by PLK4.