Description

  • Product name

    Recombinant human CEACAM6 protein
    See all CEACAM6 proteins and peptides
  • Biological activity

    Measured by the ability of the immobilized protein to support the adhesion of calcium ionophore treated Human neutrophils. When 2 x 105 cells/well are added to CEACAM6 coated plates (10 µg/mL, 100 µL/well), 45-70% of the cells will adhere after 20 minutes at 37°C.
  • Purity

    > 95 % SDS-PAGE.

  • Endotoxin level

    < 1.000 Eu/µg
  • Expression system

    HEK 293 cells
  • Accession

  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      KLTIESTPFN VAEGKEVLLL AHNLPQNRIG YSWYKGERVD GNSLIVGYVI GTQQATPGPA YSGRETIYPN ASLLIQNVTQ NDTGFYTLQV IKSDLVNEEA TGQFHVYPEL PKPSISSNNS NPVEDKDAVA FTCEPEVQNT TYLWWVNGQS LPVSPRLQLS NGNMTLTLLS VKRNDAGSYE CEIQNPASAN RSDPVTLNVL YGPDGPTISP SKANYRPGEN LNLSCHAASN PPAQYSWFIN GTFQQSTQEL FIPNITVNNS GSYMCQAHNS ATGLNRTTVT MITVSG
    • Predicted molecular weight

      32 kDa including tags
    • Amino acids

      35 to 320
    • Tags

      His tag C-Terminus

Specifications

Our Abpromise guarantee covers the use of ab167705 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Functional Studies

    SDS-PAGE

  • Form

    Lyophilised
  • Additional notes

    Measured by the ability of the immobilized protein to support the adhesion of calcium ionophore treated Human neutrophils. When 2 x 105 cells/well are added to CEACAM6 coated plates (10 µg/mL, 100 µL/well), 45-70% of the cells will adhere after 20 minutes at 37°C.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 7.40
    Constituents: 94% PBS, 5% Trehalose

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • Reconstitution
    Reconstitute the lyophilized protein in sterile deionized water to a final concentration of 400 ug/ml. Solubilize for 30 to 60 minutes at room temperature with occasional gentle mixing. Carrier protein (0.1% HSA or BSA) is strongly recommended for further dilution and long term storage.

General Info

  • Alternative names

    • Carcinoembryonic antigen related cell adhesion molecule 6
    • Carcinoembryonic antigen related cell adhesion molecule 6 (non specific cross reacting antigen)
    • Carcinoembryonic antigen-related cell adhesion molecule 6
    • CD 66c
    • CD66c
    • CD66c antigen
    • CEA LIKE PROTEIN
    • CEACAM 6
    • CEACAM6
    • CEAL
    • CEAM6_HUMAN
    • MGC93832
    • NCA
    • Non specific cross reacting antigen
    • Non-specific crossreacting antigen
    • Normal cross reacting antigen
    • Normal cross-reacting antigen
    see all
  • Sequence similarities

    Belongs to the immunoglobulin superfamily. CEA family.
    Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
    Contains 1 Ig-like V-type (immunoglobulin-like) domain.
  • Cellular localization

    Cell membrane.
  • Information by UniProt

Images

  • Human CEACAM-6, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
  • Immobilized Human CEACAM-6, His Tag at 10 µg/mL (100 µL/well) can bind Biotinylated Human CEACAM-8, His,Avitag with a linear range of 0.02-0.313 µg/mL.
  • SDS-PAGE of reduced ab167705 stained overnight with Coomassie Blue. The protein migrates as 45-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

References

ab167705 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab167705.
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