Recombinant Human CHREBP protein (ab162408)

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Overview

  • Product name
    Recombinant Human CHREBP protein
  • Protein length
    Protein fragment

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      PPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNKTENRRI THISAEQKRRFNIKLGFDTLHGLVSTLSAQPSLKVSKATTLQKTAEYI
    • Amino acids
      603 to 700
    • Tags
      proprietary tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab162408 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    ELISA

  • Form
    Liquid
  • Additional notes
    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • carbohydrate response element binding protein
    • bHLHd14
    • Carbohydrate responsive element binding protein
    • Class D basic helix-loop-helix protein 14
    • MIO
    • MLX interacting protein like
    • Mlx interactor
    • MLX-interacting protein-like
    • MLXIPL
    • MONDOB
    • WBS14_HUMAN
    • WBSCR 14
    • WBSCR14
    • Williams Beuren syndrome chromosome region 14
    • Williams Beuren syndrome chromosome region 14 protein
    • Williams-Beuren syndrome chromosomal region 14 protein
    • WS basic helix loop helix leucine zipper protein
    • WS basic-helix-loop-helix leucine zipper protein
    • WS bHLH
    • WS-bHLH
    see all
  • Function
    Transcriptional repressor. Binds to the canonical and non-canonical E box sequences 5'-CACGTG-3'.
  • Tissue specificity
    Expressed in liver, heart, kidney, cerebellum and intestinal tissues.
  • Involvement in disease
    Note=WBSCR14 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region. Haploinsufficiency of WBSCR14 may be the cause of certain cardiovascular and musculo-skeletal abnormalities observed in the disease.
  • Sequence similarities
    Contains 1 basic helix-loop-helix (bHLH) domain.
  • Cellular localization
    Nucleus.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant Human CHREBP protein (ab162408)
    SDS-PAGE - Recombinant Human CHREBP protein (ab162408)
    ab162408 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab162408 has not yet been referenced specifically in any publications.

Publishing research using ab162408? Please let us know so that we can cite the reference in this datasheet.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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