Recombinant Human CHREBP protein (ab162408)

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SDS-PAGE - Recombinant Human CHREBP protein (ab162408)

    Key features and details

    • Expression system: Wheat germ
    • Tags: GST tag N-Terminus
    • Suitable for: WB, ELISA

    Description

    • Product name

      Recombinant Human CHREBP protein

    • Expression system

      Wheat germ

    • Protein length

      Protein fragment

    • Animal free

      No

    • Nature

      Recombinant

      • Species

        Human

      • Sequence

        PPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNKTENRRI THISAEQKRRFNIKLGFDTLHGLVSTLSAQPSLKVSKATTLQKTAEYI

      • Amino acids

        603 to 700

      • Tags

        GST tag N-Terminus

    Specifications

    Our Abpromise guarantee covers the use of ab162408 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      Western blot

      ELISA

    • Form

      Liquid

    • Additional notes

       

       

    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

      pH: 8.00
      Constituents: 0.31% Glutathione, 0.79% Tris HCl

    General Info

    • Alternative names

      • carbohydrate response element binding protein
      • bHLHd14
      • Carbohydrate responsive element binding protein
      • Class D basic helix-loop-helix protein 14
      • MIO
      • MLX interacting protein like
      • Mlx interactor
      • MLX-interacting protein-like
      • MLXIPL
      • MONDOB
      • WBS14_HUMAN
      • WBSCR 14
      • WBSCR14
      • Williams Beuren syndrome chromosome region 14
      • Williams Beuren syndrome chromosome region 14 protein
      • Williams-Beuren syndrome chromosomal region 14 protein
      • WS basic helix loop helix leucine zipper protein
      • WS basic-helix-loop-helix leucine zipper protein
      • WS bHLH
      • WS-bHLH
      see all

    • Function

      Transcriptional repressor. Binds to the canonical and non-canonical E box sequences 5'-CACGTG-3'.

    • Tissue specificity

      Expressed in liver, heart, kidney, cerebellum and intestinal tissues.

    • Involvement in disease

      Note=WBSCR14 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region. Haploinsufficiency of WBSCR14 may be the cause of certain cardiovascular and musculo-skeletal abnormalities observed in the disease.

    • Sequence similarities

      Contains 1 basic helix-loop-helix (bHLH) domain.

    • Cellular localization

      Nucleus.
    • Information by UniProt

    Images

    • SDS-PAGE - Recombinant Human CHREBP protein (ab162408)
      SDS-PAGE - Recombinant Human CHREBP protein (ab162408)
      ab162408 on a 12.5% SDS-PAGE stained with Coomassie Blue.

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    References (0)

    Publishing research using ab162408? Please let us know so that we can cite the reference in this datasheet.

    ab162408 has not yet been referenced specifically in any publications.

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