Recombinant Human CHREBP protein (ab162408)

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Description

  • Product name

    Recombinant Human CHREBP protein

  • Expression system

    Wheat germ

  • Protein length

    Protein fragment

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      PPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNKTENRRI THISAEQKRRFNIKLGFDTLHGLVSTLSAQPSLKVSKATTLQKTAEYI

    • Amino acids

      603 to 700

    • Tags

      GST tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab162408 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    ELISA

  • Form

    Liquid

  • Additional notes

     

     

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names

    • carbohydrate response element binding protein
    • bHLHd14
    • Carbohydrate responsive element binding protein
    • Class D basic helix-loop-helix protein 14
    • MIO
    • MLX interacting protein like
    • Mlx interactor
    • MLX-interacting protein-like
    • MLXIPL
    • MONDOB
    • WBS14_HUMAN
    • WBSCR 14
    • WBSCR14
    • Williams Beuren syndrome chromosome region 14
    • Williams Beuren syndrome chromosome region 14 protein
    • Williams-Beuren syndrome chromosomal region 14 protein
    • WS basic helix loop helix leucine zipper protein
    • WS basic-helix-loop-helix leucine zipper protein
    • WS bHLH
    • WS-bHLH
    see all

  • Function

    Transcriptional repressor. Binds to the canonical and non-canonical E box sequences 5'-CACGTG-3'.

  • Tissue specificity

    Expressed in liver, heart, kidney, cerebellum and intestinal tissues.

  • Involvement in disease

    Note=WBSCR14 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region. Haploinsufficiency of WBSCR14 may be the cause of certain cardiovascular and musculo-skeletal abnormalities observed in the disease.

  • Sequence similarities

    Contains 1 basic helix-loop-helix (bHLH) domain.

  • Cellular localization

    Nucleus.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant Human CHREBP protein (ab162408)
    SDS-PAGE - Recombinant Human CHREBP protein (ab162408)
    ab162408 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab162408 has not yet been referenced specifically in any publications.

Publishing research using ab162408? Please let us know so that we can cite the reference in this datasheet.

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