Recombinant Human Chromogranin A protein (ab85339)

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SDS-PAGE - Recombinant Human Chromogranin A protein (ab85339)

    Key features and details

    • Expression system: Escherichia coli
    • Purity: > 95% SDS-PAGE
    • Suitable for: SDS-PAGE

    Description

    • Product name

      Recombinant Human Chromogranin A protein
      See all Chromogranin A proteins and peptides

    • Purity

      > 95 % SDS-PAGE.
      ab85339 is purified using conventional chromatography techniques. Endotoxin Level: < 1.0 EU per 1 µg of protein (determined by LAL method).

    • Expression system

      Escherichia coli

    • Protein length

      Protein fragment

    • Animal free

      No

    • Nature

      Recombinant

      • Species

        Human

      • Sequence

        MLPVNSPMNK GDTEVMKCIV EVISDTLSKP SPMPVSQECF ETLRGDERIL SILRHQNLLK ELQDLALQGA KERAHQQKKH SGFEDELSEV LENQSSQAEL KEAVEEPSSK DVME

      • Amino acids

        19 to 131

      • Additional sequence information

        This fragment is from the N terminus of Chromogranin A.

    Specifications

    Our Abpromise guarantee covers the use of ab85339 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

    • Form

      Liquid

    • Additional notes


      Vasostatin 2 is the N-terminal fragment (19-131 aa) derived from the cleavage of chromogranin A (CgA) which is a member of the chromogranin/secretogranin(granins) family of neuroendocrine secretory proteins. Vasostatin 2 has been shown to exert several biological activities on several tissues and organs and exerts a large spectrum of homeostatic actions, including antifungal and antimicrobial effect, modulation of cell adhesion, and inhibition of parathyroid hormone secretion.

    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

      pH: 8.00
      Constituents: 0.316% Tris HCl, 10% Glycerol (glycerin, glycerine)

    General Info

    • Alternative names

      • beta Granin
      • betagranin (N-terminal fragment of chromogranin A)
      • catestatin
      • CgA
      • CHG A
      • Chga
      • chromofungin
      • Chromogranin A
      • Chromogranin A parathyroid secretory protein 1
      • Chromogranin A precursor
      • ChromograninA
      • CMGA_HUMAN
      • ER-37
      • Pancreastatin
      • Parastatin
      • Parathyroid secretory protein 1
      • Pituitary secretory protein I
      • Secretory protein I
      • SP I
      • SP-I
      • SP1
      • SPI
      • Vasostatin
      • vasostatin 2
      • Vasostatin I
      • Vasostatin II
      • vasostatin-2
      see all

    • Function

      Pancreastatin strongly inhibits glucose induced insulin release from the pancreas.

    • Sequence similarities

      Belongs to the chromogranin/secretogranin protein family.

    • Post-translational
      modifications

      Sulfated on tyrosine residues and/or contains sulfated glycans.
      O-glycosylated with core 1 or possibly core 8 glycans.

    • Cellular localization

      Secreted. Neuroendocrine and endocrine secretory granules.
    • Information by UniProt

    Images

    • SDS-PAGE - Recombinant Human Chromogranin A protein (ab85339)
      SDS-PAGE - Recombinant Human Chromogranin A protein (ab85339)
      15% SDS-PAGE showing ab85339 at approximately 12.8kDa (3µg).

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    References (0)

    Publishing research using ab85339? Please let us know so that we can cite the reference in this datasheet.

    ab85339 has not yet been referenced specifically in any publications.

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