Recombinant Human Chromogranin A protein (ab85339)

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Description

  • Product name

    Recombinant Human Chromogranin A protein
    See all Chromogranin A proteins and peptides

  • Purity

    > 95 % SDS-PAGE.
    ab85339 is purified using conventional chromatography techniques. Endotoxin Level: < 1.0 EU per 1 µg of protein (determined by LAL method).

  • Expression system

    Escherichia coli

  • Protein length

    Protein fragment

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      MLPVNSPMNK GDTEVMKCIV EVISDTLSKP SPMPVSQECF ETLRGDERIL SILRHQNLLK ELQDLALQGA KERAHQQKKH SGFEDELSEV LENQSSQAEL KEAVEEPSSK DVME

    • Amino acids

      19 to 131

    • Additional sequence information

      This fragment is from the N terminus of Chromogranin A.

Specifications

Our Abpromise guarantee covers the use of ab85339 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Liquid

  • Additional notes


    Vasostatin 2 is the N-terminal fragment (19-131 aa) derived from the cleavage of chromogranin A (CgA) which is a member of the chromogranin/secretogranin(granins) family of neuroendocrine secretory proteins. Vasostatin 2 has been shown to exert several biological activities on several tissues and organs and exerts a large spectrum of homeostatic actions, including antifungal and antimicrobial effect, modulation of cell adhesion, and inhibition of parathyroid hormone secretion.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.316% Tris HCl, 10% Glycerol

General Info

  • Alternative names

    • beta Granin
    • betagranin (N-terminal fragment of chromogranin A)
    • catestatin
    • CgA
    • CHG A
    • Chga
    • chromofungin
    • Chromogranin A
    • Chromogranin A parathyroid secretory protein 1
    • Chromogranin A precursor
    • ChromograninA
    • CMGA_HUMAN
    • ER-37
    • Pancreastatin
    • Parastatin
    • Parathyroid secretory protein 1
    • Pituitary secretory protein I
    • Secretory protein I
    • SP I
    • SP-I
    • SP1
    • SPI
    • Vasostatin
    • vasostatin 2
    • Vasostatin I
    • Vasostatin II
    • vasostatin-2
    see all

  • Function

    Pancreastatin strongly inhibits glucose induced insulin release from the pancreas.

  • Sequence similarities

    Belongs to the chromogranin/secretogranin protein family.

  • Post-translational
    modifications

    Sulfated on tyrosine residues and/or contains sulfated glycans.
    O-glycosylated with core 1 or possibly core 8 glycans.

  • Cellular localization

    Secreted. Neuroendocrine and endocrine secretory granules.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant Human Chromogranin A protein (ab85339)
    SDS-PAGE - Recombinant Human Chromogranin A protein (ab85339)
    15% SDS-PAGE showing ab85339 at approximately 12.8kDa (3µg).

References

ab85339 has not yet been referenced specifically in any publications.

Publishing research using ab85339? Please let us know so that we can cite the reference in this datasheet.

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