Overview

Description

  • Nature

    Recombinant
  • Source

    HEK 293 cells
  • Amino Acid Sequence
    • Accession
    • Species

      Human
    • Sequence

      CGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIAS NFVLTAAHCISNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNAL LLRNDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTN GPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGVISACNGDS GGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKM QLVDHHHHHH
    • Molecular weight

      29 kDa including tags
    • Amino acids

      17 to 268
    • Tags

      His tag C-Terminus

Specifications

Our Abpromise guarantee covers the use of ab151677 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    HPLC

  • Endotoxin level

    < 1.000 Eu/µg
  • Purity

    > 95 % SDS-PAGE.
    ab151677 is greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. It is supplied as a 0.2 µM filtered solution.
  • Form

    Liquid
  • Additional notes

    Biological activity: Not determined. Customer feedback suggests no cleaving ability.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. After reconstitution store at -20ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 0.88% Sodium chloride

General Info

  • Alternative names

    • Caldecrin
    • Chymotrypsin C
    • Chymotrypsin-C
    • ChymotrypsinC
    • CLCR
    • Ctrc
    • CTRC_HUMAN
    • ELA 4
    • ELA4
    • Elastase 4
    • Elastase IV
    • Elastase4
    • ElastaseIV
    • OTTHUMP00000044526
    • Serum calcium decreasing factor
    see all
  • Function

    Has chymotrypsin-type protease activity and hypocalcemic activity.
  • Tissue specificity

    Pancreas.
  • Involvement in disease

    Variations in CTRC influence susceptibility to chronic pancreatitis [MIM:167800]. Chronic pancreatitis is a persistent inflammatory disorder characterized by permanent destruction of the pancreatic parenchyma.
  • Sequence similarities

    Belongs to the peptidase S1 family. Elastase subfamily.
    Contains 1 peptidase S1 domain.
  • Information by UniProt

References

ab151677 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab151677.
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