Overview

  • Product name

    Recombinant Human CIAO1 protein
  • Protein length

    Full length protein

Description

  • Nature

    Recombinant
  • Source

    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species

      Human
    • Sequence

      MGSSHHHHHH SSGLVPRGSH MGSMKDSLVL LGRVPAHPDS RCWFLAWNPA GTLLASCGGD RRIRIWGTEG DSWICKSVLS EGHQRTVRKV AWSPCGNYLA SASFDATTCI WKKNQDDFEC VTTLEGHENE VKSVAWAPSG NLLATCSRDK SVWVWEVDEE DEYECVSVLN SHTQDVKHVV WHPSQELLAS ASYDDTVKLY REEEDDWVCC ATLEGHESTV WSLAFDPSGQ RLASCSDDRT VRIWRQYLPG NEQGVACSGS DPSWKCICTL SGFHSRTIYD IAWCQLTGAL ATACGDDAIR VFQEDPNSDP QQPTFSLTAH LHQAHSQDVN CVAWNPKEPG LLASCSDDGE VAFWKYQRPE GL
    • Molecular weight

      40 kDa including tags
    • Amino acids

      1 to 339
    • Tags

      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab140542 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Mass Spectrometry

  • Mass spectrometry

    MALDI-TOF
  • Purity

    > 95 % SDS-PAGE.
    ab140542 is purified using conventional chromatography techniques.
  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.02% DTT, 0.32% Tris HCl, 20% Glycerol, 0.88% Sodium chloride

General Info

  • Alternative names

    • Ciao 1 protein
    • CIAO1
    • WD repeat domain 39
    • WD40 Protein Ciao 1
    • WDR39
    • WDR39 protein
    see all
  • Relevance

    CIAO1 (named after the Chinese word for bridge) is capable of modulating the transcriptional activities of WT1, the Wilm tumour gene. CIAO1 is a 339-amino acid polypeptide containing 7 WD40 or beta-transducin repeats. It can inhibit the transcriptional activation function of WT1, but does not affect WT1-mediated transcriptional repression. The yeast CIAO1 homolog is an essential protein that appears to be highly evolutionarily conserved.
  • Cellular localization

    Nuclear

Images

  • 15% SDS-PAGE analysis of ab140542 (3ug)

References

ab140542 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab140542.
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